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EC
EcoR1 Capital Portfolio holdings
AUM
$2.34B
1-Year Est. Return
204.53%
This Fund
S&P 500
This Quarter
Est. Return
-11.09%
1 Year Est. Return
+204.53%
3 Year Est. Return
+306.25%
5 Year Est. Return
+490.45%
10 Year Est. Return
+14,115.48%
AUM
$2.94B
AUM Growth
-$859M
(-23%)
Cap. Flow
-$87.3M
Cap. Flow
% of AUM
-2.97%
Top 10 Holdings %
Top 10 Hldgs %
73.2%
Holding
58
New
6
Increased
6
Reduced
4
Closed
8
Top Buys
| 1 |
APLS
Apellis Pharmaceuticals
APLS
|
+$239M |
| 2 |
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
|
+$205M |
| 3 |
MRSN
Mersana Therapeutics
MRSN
|
+$36.8M |
| 4 |
Arvinas
ARVN
|
+$35.6M |
| 5 |
SLRN
ACELYRIN
SLRN
|
+$29.8M |
Top Sells
| 1 |
Sarepta Therapeutics
SRPT
|
+$419M |
| 2 |
MORF
Morphic Holding, Inc. Common Stock
MORF
|
+$124M |
| 3 |
BPMC
Blueprint Medicines
BPMC
|
+$114M |
| 4 |
Revolution Medicines
RVMD
|
+$48.1M |
| 5 |
Dyne Therapeutics
DYN
|
+$8.99M |
Sector Composition
| 1 | Healthcare | 99.93% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
1
Prothena Corp
PRTA
$450M
| $559M | 19.04% |
11,584,280
| – | – |
|
|
APLS
2
DELISTED
Apellis Pharmaceuticals
APLS
| $415M | 14.12% |
10,899,859
+5,448,212
| +100% | +$239M |
|
|
MRTX
3
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
| $250M | 8.53% |
+5,748,399
| New | +$205M |
|
|
LKFT
4
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.94B
| $199M | 6.77% |
5,756,268
| – | – |
|
|
5
Revolution Medicines
RVMD
$39.3B
| $154M | 5.26% |
5,577,863
-1,620,837
| -23% | -$48.1M |
|
6
AnaptysBio
ANAB
$1.67B
| $135M | 4.6% |
7,521,024
| – | – |
|
7
Acadia Pharmaceuticals
ACAD
$4.44B
| $125M | 4.25% |
5,991,479
| – | – |
|
|
8
Arvinas
ARVN
$536M
| $107M | 3.66% |
5,467,063
+1,449,275
| +36% | +$35.6M |
|
9
Xencor
XNCR
$1.11B
| $106M | 3.63% |
5,282,516
| – | – |
|
10
Tango Therapeutics
TNGX
$4.95B
| $98.2M | 3.34% |
8,721,636
+4,674,522
| +116% | +$28.5M |
|
11
Zymeworks
ZYME
$1.82B
| $85.2M | 2.9% |
13,437,473
| – | – |
|
|
SWTX
12
DELISTED
SpringWorks Therapeutics
SWTX
| $80M | 2.72% |
3,460,208
| – | – |
|
13
Kura Oncology
KURA
$1B
| $53M | 1.8% |
5,806,871
| – | – |
|
14
Jazz Pharmaceuticals
JAZZ
$15.1B
| $47.7M | 1.62% |
368,411
| – | – |
|
15
Crinetics Pharmaceuticals
CRNX
$8.88B
| $45.5M | 1.55% |
1,530,263
+200,000
| +15% | +$4.12M |
|
|
CNTA
16
DELISTED
Centessa Pharmaceuticals
CNTA
| $36.4M | 1.24% |
5,618,779
| – | – |
|
17
Relay Therapeutics
RLAY
$4.24B
| $35M | 1.19% |
4,163,824
| – | – |
|
|
MORF
18
DELISTED
Morphic Holding, Inc. Common Stock
MORF
| $33.9M | 1.16% |
1,480,190
-2,366,774
| -62% | -$124M |
|
19
Voyager Therapeutics
VYGR
$193M
| $29.8M | 1.02% |
3,851,507
| – | – |
|
20
Neumora Therapeutics
NMRA
$304M
| $29.2M | 1% |
+2,071,450
| New | +$25.9M |
|
21
Alector
ALEC
$167M
| $26.3M | 0.9% |
4,056,548
| – | – |
|
22
Nuvation Bio
NUVB
$2.03B
| $25.7M | 0.88% |
19,209,643
+5,313,100
| +38% | +$8.84M |
|
|
MRSN
23
DELISTED
Mersana Therapeutics
MRSN
| $24.6M | 0.84% |
+774,588
| New | +$36.8M |
|
24
Ovid Therapeutics
OVID
$467M
| $23.5M | 0.8% |
6,117,400
| – | – |
|
|
LENZ
25
LENZ Therapeutics
LENZ
$151M
| $21.2M | 0.72% |
1,219,778
| – | – |
|
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