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EC

EcoR1 Capital Portfolio holdings

AUM $2.06B
1-Year Est. Return 215.32%
This Fund
S&P 500
This Quarter Est. Return
+13.6%
1 Year Est. Return
+215.32%
3 Year Est. Return
+310.3%
5 Year Est. Return
+497.45%
10 Year Est. Return
+14,692.23%
AUM
$300M
AUM Growth
-$135K
Cap. Flow
-$18M
Cap. Flow %
-6.01%
Top 10 Hldgs %
82.64%
Holding
32
New
9
Increased
4
Reduced
2
Closed
7
Avg Time Held Equity + Options
1.1 quarters
Top 10 Avg Time Held Equity + Options
0.9 quarters
Top 20 Avg Time Held Equity + Options
1.1 quarters
Avg Time Held Equity only
1.2 quarters
Top 10 Avg Time Held Equity only
1.1 quarters
Top 20 Avg Time Held Equity only
1.2 quarters

Top Buys

Rank Stock Value
1
KYNB icon
Kyntra Bio
KYNB
+$18.7M
2
ATYR icon
aTyr Pharma
ATYR
+$18.6M
3
EIGR
Eiger BioPharmaceuticals, Inc.
EIGR
+$17.5M
4
COLL icon
Collegium Pharmaceutical
COLL
+$8.04M
5
ARRY icon
Array Biopharma Inc
ARRY
+$2.95M

Top Sells

Rank Stock Value
1
RCPT
RECEPTOS INC COM STK (DE)
RCPT
+$24.9M
2
CLVS
Clovis Oncology, Inc.
CLVS
+$18M
3
IRWD icon
Ironwood Pharmaceuticals
IRWD
+$14.4M
4
SAGE icon
Sage Therapeutics
SAGE
+$5.65M
5
FLXN icon
Flexion Therapeutics, Inc.
FLXN
+$3.67M

Sector Composition

Rank Sector Weight
1 Healthcare 85.8%
2 Miscellaneous 14.2%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow Held Since
ATRA icon
1
Atara Biotherapeutics
ATRA
$94.5M
$56.1M 18.7%
42,528
– –
2014 Q4
2 quarters
EPZM
2
DELISTED
Epizyme, Inc
EPZM
$40.5M 13.49%
1,685,800
+105,400
+7% +$2.03M
2015 Q1
1 quarter
ASMB icon
3
Assembly Biosciences
ASMB
$415M
$30.3M 10.11%
131,176
– –
2014 Q4
2 quarters
KYNB icon
4
Kyntra Bio
KYNB
$23.6M
$28.3M 9.44%
48,216
+32,216
+201% +$18.7M
2014 Q4
2 quarters
KITE
5
DELISTED
Kite Pharma, Inc.
KITE
$17.2M 5.72%
281,400
– –
2014 Q4
2 quarters
DCOY icon
6
Decoy Therapeutics
DCOY
$773K
$15.6M 5.21%
1
– –
2015 Q1
1 quarter
ATYR icon
7
aTyr Pharma
ATYR
$18.9M
$15.5M 5.17%
+59,776
New +$18.6M
2015 Q2
0 quarters
TVTX icon
8
Travere Therapeutics
TVTX
$4.99B
$11.3M 3.78%
341,650
-68,350
-17% -$1.87M
2015 Q1
1 quarter
KIN
9
DELISTED
Kindred Biosciences, Inc.
KIN
$8.83M 2.94%
1,294,431
– –
2014 Q4
2 quarters
COLL icon
10
Collegium Pharmaceutical
COLL
$731M
$8.3M 2.77%
+465,118
New +$8.04M
2015 Q2
0 quarters
ARRY icon
11
CALL
DELISTED
Array Biopharma Inc
ARRY
$7.93M 2.64%
11,000
+3,650
+50% +$26.9K
2014 Q4
2 quarters
TPST icon
12
CALL
Tempest Therapeutics
TPST
$11M
$6.65M 2.22%
+1
New +$91.6K
2015 Q2
0 quarters
FWP
13
DELISTED
Forward Pharma A/S American Depositary Shares
FWP
$6.05M 2.02%
22,712
– –
2014 Q4
2 quarters
GNVC
14
DELISTED
GenVec, Inc.
GNVC
$4.05M 1.35%
198,641
– –
2014 Q4
2 quarters
EIGR
15
DELISTED
Eiger BioPharmaceuticals, Inc.
EIGR
$3.58M 1.19%
+6,318
New +$17.5M
2015 Q2
0 quarters
CALA
16
DELISTED
Calithera Biosciences, Inc
CALA
$2.97M 0.99%
20,774
+6,000
+41% +$1.39M
2014 Q4
2 quarters
ARRY icon
17
DELISTED
Array Biopharma Inc
ARRY
$2.88M 0.96%
+400,000
New +$2.95M
2015 Q2
0 quarters
BITI icon
18
DELISTED
BIOTIE THERAPIES CORP SPONSORED ADR
BITI
$2M 0.67%
+100,000
New +$2.09M
2015 Q2
0 quarters
GYRE icon
19
Gyre Therapeutics
GYRE
$700M
$1.73M 0.58%
787
– –
2014 Q4
2 quarters
MCRB icon
20
Seres Therapeutics
MCRB
$24.5M
$1.66M 0.55%
+2,000
New +$1.75M
2015 Q2
0 quarters
QLTI icon
21
DELISTED
QLT Inc
QLTI
$1.65M 0.55%
+400,000
New +$1.54M
2015 Q2
0 quarters
RGLS icon
22
CALL
DELISTED
Regulus Therapeutics
RGLS
$1.4M 0.47%
+11
New +$17.8K
2015 Q2
0 quarters
XENE icon
23
Xenon Pharmaceuticals
XENE
$3.26B
$842K 0.28%
73,000
-147,570
-67% -$2.04M
2014 Q4
2 quarters
EPZM
24
CALL
DELISTED
Epizyme, Inc
EPZM
$360K 0.12%
150
– –
2015 Q1
1 quarter
IRWD icon
25
CALL
Ironwood Pharmaceuticals
IRWD
$598M
– –
-5,970
Closed -$8M –
1
2

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EcoR1 Capital's Q2 2015 Portfolio in Review

As of Q2 2015, EcoR1 Capital held 32 positions worth $300M, down 0.04% from $300M the previous quarter. Its ten largest holdings account for 83% of the portfolio.

EcoR1 Capital withdrew a net $18M in Q2 2015, closing 7 positions and reducing 2 holdings. Its most notable exit was RECEPTOS INC COM STK (DE), an estimated $24.9M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 86% of assets, up from 74% a quarter earlier, followed by Miscellaneous.

Against the trend, EcoR1 Capital opened a new position in aTyr Pharma worth $15.5M.

  • EcoR1 Capital's largest Q2 2015 buy was aTyr Pharma: 59,776 shares worth $15.5M.
  • EcoR1 Capital added most to Kyntra Bio in Q2 2015, an estimated $18.7M increase.
  • EcoR1 Capital's biggest Q2 2015 reduction was Xenon Pharmaceuticals, cutting an estimated $2.04M.
  • EcoR1 Capital fully exited RECEPTOS INC COM STK (DE) in Q2 2015, selling an estimated $24.9M.
  • EcoR1 Capital's ten largest holdings make up 83% of its $300M portfolio in Q2 2015.
  • EcoR1 Capital opened 9 new positions and closed 7 in Q2 2015.
  • EcoR1 Capital's portfolio value fell 0.04% quarter-over-quarter to $300M.

Based on EcoR1 Capital's 13F filing for Q2 2015, filed 14 Aug 2015.