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EcoR1 Capital Portfolio holdings

AUM $2.06B
1-Year Est. Return 215.32%
This Fund
S&P 500
This Quarter Est. Return
+14.51%
1 Year Est. Return
+215.32%
3 Year Est. Return
+310.3%
5 Year Est. Return
+497.45%
10 Year Est. Return
+14,692.23%
AUM
$997M
AUM Growth
+$109M
Cap. Flow
+$118M
Cap. Flow %
11.83%
Top 10 Hldgs %
74.49%
Holding
41
New
11
Increased
8
Reduced
8
Closed
10
Avg Time Held Equity + Options
2.9 quarters
Top 10 Avg Time Held Equity + Options
3.7 quarters
Top 20 Avg Time Held Equity + Options
2.5 quarters
Avg Time Held Equity only
3.1 quarters
Top 10 Avg Time Held Equity only
3.7 quarters
Top 20 Avg Time Held Equity only
2.7 quarters

Sector Composition

Rank Sector Weight
1 Healthcare 93.61%
2 Miscellaneous 6.39%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
ASMB icon
1
Assembly Biosciences
ASMB
$414M
$145M 14.51%
245,264
– –
2014 Q4
13 quarters
ASND icon
2
Ascendis Pharma A/S
ASND
$14.7B
$119M 11.96%
1,822,575
-285,025
-14% -$16M
2016 Q3
6 quarters
KYNB icon
3
Kyntra Bio
KYNB
$23.8M
$92.5M 9.28%
80,097
-1,812
-2% -$2.39M
2014 Q4
13 quarters
IRWD icon
4
Ironwood Pharmaceuticals
IRWD
$593M
$90.8M 9.11%
7,027,386
– –
2015 Q4
9 quarters
KURA icon
5
Kura Oncology
KURA
$874M
$70.6M 7.08%
3,766,852
– –
2015 Q4
9 quarters
WVE icon
6
Wave Life Sciences
WVE
$619M
$58.5M 5.87%
1,459,072
+522,909
+56% +$22M
2017 Q3
2 quarters
ARRY icon
7
DELISTED
Array Biopharma Inc
ARRY
$49.8M 4.99%
3,049,312
+166,600
+6% +$2.67M
2017 Q3
2 quarters
DRNA
8
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
$45.5M 4.57%
4,764,447
-72,100
-1% -$777K
2017 Q1
4 quarters
MGNX icon
9
MacroGenics
MGNX
$218M
$36.5M 3.66%
1,450,606
+309,812
+27% +$7.53M
2017 Q4
1 quarter
RCUS icon
10
Arcus Biosciences
RCUS
$2.87B
$34.5M 3.46%
+2,236,387
New +$37.3M
2018 Q1
0 quarters
CELG
11
CALL
DELISTED
Celgene Corp
CELG
$34.3M 3.44%
385,000
-490,000
-56% -$47M
2017 Q4
1 quarter
APLS icon
12
DELISTED
Apellis Pharmaceuticals
APLS
$23.4M 2.34%
1,056,348
-88,210
-8% -$1.73M
2017 Q4
1 quarter
FPRX
13
DELISTED
Five Prime Therapeutics, Inc.
FPRX
$21.3M 2.14%
+1,240,470
New +$24.2M
2018 Q1
0 quarters
URGN icon
14
UroGen Pharma
URGN
$1.87B
$20M 2.01%
+402,300
New +$20.2M
2018 Q1
0 quarters
KYNB icon
15
CALL
Kyntra Bio
KYNB
$23.8M
$15M 1.51%
13,000
+1,584
+14% +$2.09M
2017 Q4
1 quarter
IMDZ
16
DELISTED
Immune Design Corp.
IMDZ
$14.4M 1.45%
4,437,600
+875,000
+25% +$3.1M
2017 Q4
1 quarter
AGIO icon
17
Agios Pharmaceuticals
AGIO
$1.8B
$14.1M 1.42%
+172,952
New +$13.4M
2018 Q1
0 quarters
AKBA icon
18
Akebia Therapeutics
AKBA
$213M
$13.6M 1.36%
+1,425,000
New +$19.9M
2018 Q1
0 quarters
ACHN
19
DELISTED
Achillion Pharmaceuticals
ACHN
$13.6M 1.36%
3,668,307
+1,827,582
+99% +$5.98M
2017 Q4
1 quarter
DOVA
20
DELISTED
Dova Pharmaceuticals, Inc. Common Stock
DOVA
$11.7M 1.17%
+429,729
New +$12.9M
2018 Q1
0 quarters
ATYR icon
21
aTyr Pharma
ATYR
$19.7M
$10.6M 1.06%
279,855
– –
2016 Q4
5 quarters
DBVT icon
22
DBV Technologies S.A. American Depositary Shares
DBVT
$568M
$10.4M 1.04%
+45,000
New +$10.6M
2018 Q1
0 quarters
IRWD icon
23
CALL
Ironwood Pharmaceuticals
IRWD
$593M
$10.3M 1.03%
797,353
+200,353
+34% +$2.5M
2017 Q3
2 quarters
PTGX icon
24
Protagonist Therapeutics
PTGX
$8.96B
$9.31M 0.93%
+1,083,567
New +$20.4M
2018 Q1
0 quarters
SYBX icon
25
DELISTED
Synlogic
SYBX
$6.57M 0.66%
+46,667
New +$7.23M
2018 Q1
0 quarters

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EcoR1 Capital's Q1 2018 Portfolio in Review

As of Q1 2018, EcoR1 Capital held 41 positions worth $997M, up 12% from $888M the previous quarter. Its ten largest holdings account for 74% of the portfolio.

EcoR1 Capital deployed $118M of net new capital in Q1 2018, opening 11 new positions and adding to 8 existing holdings. Its largest new stake was Arcus Biosciences: 2,236,387 shares worth $34.5M.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, up from 84% a quarter earlier, followed by Miscellaneous.

On the sell side, the largest reduction was Ascendis Pharma A/S, an estimated $16M trimmed.

  • EcoR1 Capital's largest Q1 2018 buy was Arcus Biosciences: 2,236,387 shares worth $34.5M.
  • EcoR1 Capital added most to Wave Life Sciences in Q1 2018, an estimated $22M increase.
  • EcoR1 Capital's biggest Q1 2018 reduction was Ascendis Pharma A/S, cutting an estimated $16M.
  • EcoR1 Capital fully exited MyoKardia, Inc. Common Stock in Q1 2018, selling an estimated $32.8M.
  • EcoR1 Capital's ten largest holdings make up 74% of its $997M portfolio in Q1 2018.
  • EcoR1 Capital opened 11 new positions and closed 10 in Q1 2018.
  • EcoR1 Capital's portfolio value rose 12% quarter-over-quarter to $997M.

Based on EcoR1 Capital's 13F filing for Q1 2018, filed 15 May 2018.