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EC

EcoR1 Capital Portfolio holdings

AUM $2.34B
1-Year Est. Return 204.53%
This Fund
S&P 500
This Quarter Est. Return
-12.44%
1 Year Est. Return
+204.53%
3 Year Est. Return
+306.25%
5 Year Est. Return
+490.45%
10 Year Est. Return
+14,115.48%
AUM
$3.27B
AUM Growth
-$670M
Cap. Flow
+$21.7M
Cap. Flow %
0.66%
Top 10 Hldgs %
61.39%
Holding
63
New
6
Increased
5
Reduced
5
Closed
8

Top Buys

1
MORF
Morphic Holding, Inc. Common Stock
MORF
+$77M
2
JANX icon
Janux Therapeutics
JANX
+$69M
3
CRGX
CARGO Therapeutics
CRGX
+$27.9M
4
BCYC
Bicycle Therapeutics
BCYC
+$20.6M
5
ITOS
iTeos Therapeutics
ITOS
+$17.9M

Top Sells

1
ACAD icon
Acadia Pharmaceuticals
ACAD
+$75M
2
SRPT icon
Sarepta Therapeutics
SRPT
+$65.8M
3
ALEC icon
Alector
ALEC
+$24.4M
4
NKTX icon
Nkarta
NKTX
+$21.6M
5
OVID icon
Ovid Therapeutics
OVID
+$18.7M

Sector Composition

1 Healthcare 99.88%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
APLS
1
DELISTED
Apellis Pharmaceuticals
APLS
$445M 13.62%
11,607,425
+250,000
+2% +$11.3M
PRTA icon
2
Prothena Corp
PRTA
$450M
$239M 7.31%
11,584,280
– –
SRPT icon
3
Sarepta Therapeutics
SRPT
$1.83B
$222M 6.8%
1,407,322
-512,513
-27% -$65.8M
ANAB icon
4
AnaptysBio
ANAB
$1.67B
$188M 5.77%
7,521,024
– –
CRNX icon
5
Crinetics Pharmaceuticals
CRNX
$8.88B
$186M 5.69%
4,155,375
– –
ARVN icon
6
Arvinas
ARVN
$536M
$179M 5.48%
6,726,491
– –
MORF
7
DELISTED
Morphic Holding, Inc. Common Stock
MORF
$170M 5.19%
4,982,945
+2,598,561
+109% +$77M
LKFT
8
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.94B
$143M 4.36%
5,756,268
– –
KURA icon
9
Kura Oncology
KURA
$1B
$120M 3.66%
5,806,871
– –
TNGX icon
10
Tango Therapeutics
TNGX
$4.95B
$114M 3.5%
13,330,736
– –
ZYME icon
11
Zymeworks
ZYME
$1.82B
$114M 3.5%
13,437,473
– –
JAZZ icon
12
Jazz Pharmaceuticals
JAZZ
$15.1B
$108M 3.31%
1,013,952
– –
XNCR icon
13
Xencor
XNCR
$1.11B
$101M 3.09%
5,330,416
– –
CRSP icon
14
CRISPR Therapeutics
CRSP
$5.03B
$75M 2.3%
1,389,276
– –
JANX icon
15
Janux Therapeutics
JANX
$969M
$61.6M 1.88%
+1,469,818
New +$69M
NUVB icon
16
Nuvation Bio
NUVB
$2.03B
$56.1M 1.72%
19,209,643
– –
CNTA
17
DELISTED
Centessa Pharmaceuticals
CNTA
$51.6M 1.58%
5,714,404
+95,625
+2% +$907K
ITOS
18
DELISTED
iTeos Therapeutics
ITOS
$48.2M 1.48%
3,249,835
+1,250,586
+63% +$17.9M
IMNM icon
19
Immunome
IMNM
$2.58B
$46.9M 1.44%
3,879,415
– –
NGNE icon
20
Neurogene
NGNE
$794M
$46.3M 1.42%
1,271,342
– –
THRD
21
DELISTED
Third Harmonic Bio
THRD
$41.4M 1.27%
3,182,444
– –
MRSN
22
DELISTED
Mersana Therapeutics
MRSN
$38.9M 1.19%
774,588
– –
VYGR icon
23
Voyager Therapeutics
VYGR
$193M
$31M 0.95%
3,917,546
– –
RNAM
24
DELISTED
Avidity Biosciences
RNAM
$30.9M 0.95%
757,576
– –
TCRX icon
25
TScan Therapeutics
TCRX
$60.3M
$29.3M 0.89%
5,000,000
– –
1
2 3

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