EC

EcoR1 Capital Portfolio holdings

AUM $2.06B Turnover 46.34%
1-Year Est. Return 215.32%
This Fund
S&P 500
This Quarter Est. Return
+27.98%
1 Year Est. Return
+215.32%
3 Year Est. Return
+310.3%
5 Year Est. Return
+497.45%
10 Year Est. Return
+14,692.23%
AUM
$300M
AUM Growth
+$102M
Cap. Flow
+$5.36M
Cap. Flow %
1.79%
Top 10 Hldgs %
74.87%
Holding
29
New
7
Increased
5
Reduced
5
Closed
6
Avg Time Held Equity + Options
0.2 years
Top 10 Avg Time Held Equity + Options
0.2 years
Top 20 Avg Time Held Equity + Options
0.2 years
Avg Time Held Equity only
0.2 years
Top 10 Avg Time Held Equity only
0.2 years
Top 20 Avg Time Held Equity only
0.2 years

Top Buys

Rank Stock Value
1
EPZM
Epizyme, Inc
EPZM
+$32.6M
2
ATRA icon
Atara Biotherapeutics
ATRA
+$17.9M
3
DCOY icon
Decoy Therapeutics
DCOY
+$15.5M
4
ASMB icon
Assembly Biosciences
ASMB
+$6.36M
5
TVTX icon
Travere Therapeutics
TVTX
+$6.25M

Top Sells

Rank Stock Value
1
SAGE icon
Sage Therapeutics
SAGE
+$16.3M
2
MGNX icon
MacroGenics
MGNX
+$15.9M
3
KITE
Kite Pharma, Inc.
KITE
+$10.5M
4
CLVS
Clovis Oncology, Inc.
CLVS
+$9.98M
5
VTAE
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
+$3.44M

Sector Composition

Rank Sector Weight
1 Healthcare 73.61%
2 Miscellaneous 26.39%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow Held Since
ATRA icon
1
Atara Biotherapeutics
ATRA
$96M
$44.2M 14.73%
42,528
+27,123
+176% +$17.9M
2014 Q4
1 quarter
EPZM
2
DELISTED
Epizyme, Inc
EPZM
$29.7M 9.89%
+1,580,400
New +$32.6M
2015 Q1
0 quarters
RCPT
3
DELISTED
RECEPTOS INC COM STK (DE)
RCPT
$24.9M 8.31%
151,301
+5,500
+4% +$696K
2014 Q4
1 quarter
ASMB icon
4
Assembly Biosciences
ASMB
$418M
$20.8M 6.95%
131,176
+47,030
+56% +$6.36M
2014 Q4
1 quarter
CLVS
5
PUT
DELISTED
Clovis Oncology, Inc.
CLVS
$18.6M 6.18%
+2,500
New +$177K
2015 Q1
0 quarters
CLVS
6
DELISTED
Clovis Oncology, Inc.
CLVS
$18M 6.01%
243,048
-141,300
-37% -$9.98M
2014 Q4
1 quarter
KITE
7
DELISTED
Kite Pharma, Inc.
KITE
$16.2M 5.41%
281,400
-157,000
-36% -$10.5M
2014 Q4
1 quarter
DCOY icon
8
Decoy Therapeutics
DCOY
$767K
$15.8M 5.26%
+1
New +$15.5M
2015 Q1
0 quarters
IRWD icon
9
Ironwood Pharmaceuticals
IRWD
$595M
$14.4M 4.8%
1,074,600
– –
2014 Q4
1 quarter
KYNB icon
10
Kyntra Bio
KYNB
$22.6M
$12.6M 4.18%
16,000
– –
2014 Q4
1 quarter
TVTX icon
11
Travere Therapeutics
TVTX
$5.02B
$9.82M 3.27%
+410,000
New +$6.25M
2015 Q1
0 quarters
KIN
12
DELISTED
Kindred Biosciences, Inc.
KIN
$9.24M 3.08%
1,294,431
– –
2014 Q4
1 quarter
IRWD icon
13
CALL
Ironwood Pharmaceuticals
IRWD
$595M
$8M 2.67%
+5,970
New +$78.3K
2015 Q1
0 quarters
GNVC
14
DELISTED
GenVec, Inc.
GNVC
$5.86M 1.95%
198,641
– –
2014 Q4
1 quarter
SAGE icon
15
DELISTED
Sage Therapeutics
SAGE
$5.65M 1.88%
112,455
-378,589
-77% -$16.3M
2014 Q4
1 quarter
ARRY icon
16
CALL
DELISTED
Array Biopharma Inc
ARRY
$5.42M 1.81%
7,350
-221,050
-97% -$1.57M
2014 Q4
1 quarter
CALA
17
DELISTED
Calithera Biosciences, Inc
CALA
$4.85M 1.62%
14,774
+4,689
+46% +$1.67M
2014 Q4
1 quarter
FWP
18
DELISTED
Forward Pharma A/S American Depositary Shares
FWP
$4.5M 1.5%
22,712
+8,426
+59% +$1.37M
2014 Q4
1 quarter
XENE icon
19
Xenon Pharmaceuticals
XENE
$3.28B
$3.72M 1.24%
220,570
-107,500
-33% -$1.99M
2014 Q4
1 quarter
FLXN icon
20
DELISTED
Flexion Therapeutics, Inc.
FLXN
$3.67M 1.22%
+162,900
New +$3.77M
2015 Q1
0 quarters
GYRE icon
21
Gyre Therapeutics
GYRE
$686M
$1.84M 0.61%
787
– –
2014 Q4
1 quarter
EPZM
22
CALL
DELISTED
Epizyme, Inc
EPZM
$282K 0.09%
+150
New +$3.1K
2015 Q1
0 quarters
HALO icon
23
CALL
Halozyme
HALO
$13.3B
– –
-160,700
Closed -$1.55M –
MGNX icon
24
MacroGenics
MGNX
$211M
– –
-453,626
Closed -$15.9M –
PRTK
25
DELISTED
Paratek Pharmaceuticals, Inc.
PRTK
– –
-78,958
Closed -$3.04M –
1
2

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EcoR1 Capital's Q1 2015 Portfolio in Review

As of Q1 2015, EcoR1 Capital held 29 positions worth $300M, up 52% from $198M the previous quarter. Its ten largest holdings account for 75% of the portfolio.

EcoR1 Capital's Q1 2015 filing shows 7 new, 5 increased, 5 reduced and 6 closed positions. Its largest new stake was Epizyme, Inc: 1,580,400 shares worth $29.7M. The largest sale was Sage Therapeutics, an estimated $16.3M.

By sector, the portfolio is most concentrated in Healthcare at 74% of assets, down from 75% a quarter earlier, followed by Miscellaneous.

  • EcoR1 Capital's largest Q1 2015 buy was Epizyme, Inc: 1,580,400 shares worth $29.7M.
  • EcoR1 Capital added most to Atara Biotherapeutics in Q1 2015, an estimated $17.9M increase.
  • EcoR1 Capital's biggest Q1 2015 reduction was Sage Therapeutics, cutting an estimated $16.3M.
  • EcoR1 Capital fully exited MacroGenics in Q1 2015, selling an estimated $15.9M.
  • EcoR1 Capital's ten largest holdings make up 75% of its $300M portfolio in Q1 2015.
  • EcoR1 Capital opened 7 new positions and closed 6 in Q1 2015.
  • EcoR1 Capital's portfolio value rose 52% quarter-over-quarter to $300M.

Based on EcoR1 Capital's 13F filing for Q1 2015, filed 15 May 2015.