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EcoR1 Capital’s Tango Therapeutics TNGX Stock Holding History

EcoR1 Capital’s Portfolio TNGX Stock Details TNGX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-10,630,736
Closed -$89.3M – 40
2025
Q3 		$89.3M Hold
10,630,736
– – 4.29% 7
2025
Q2 		$54.4M Hold
10,630,736
– – 3.22% 9
2025
Q1 		$14.6M Hold
10,630,736
– – 0.86% 21
2024
Q4 		$32.8M Sell
10,630,736
-2,700,000
-20% -$12.5M 1.24% 17
2024
Q3 		$103M Hold
13,330,736
– – 3.51% 10
2024
Q2 		$114M Hold
13,330,736
– – 3.5% 10
2024
Q1 		$106M Hold
13,330,736
– – 2.68% 13
2023
Q4 		$132M Buy
13,330,736
+4,609,100
+53% +$40M 3.43% 9
2023
Q3 		$98.2M Buy
8,721,636
+4,674,522
+116% +$28.5M 3.31% 10
2023
Q2 		$13.4M Sell
4,047,114
-154,300
-4% -$555K 0.33% 30
2023
Q1 		$16.6M Hold
4,201,414
– – 0.53% 30
2022
Q4 		$30.5M Hold
4,201,414
– – 0.93% 20
2022
Q3 		$15.2M Buy
4,201,414
+1,899,349
+83% +$8.11M 0.45% 30
2022
Q2 		$10.4M Buy
2,302,065
+1,540,094
+202% +$9.32M 0.36% 39
2022
Q1 		$5.78M Sell
761,971
-538,029
-41% -$4.66M 0.18% 48
2021
Q4 		$14.2M Hold
1,300,000
– – 0.45% 34
2021
Q3 		$16.8M Buy
1,300,000
+500,000
+63% +$5.99M 0.58% 27
2021
Q2 		$9.1M Hold
800,000
– – 0.34% 35
2021
Q1 		$8.9M Hold
800,000
– – 0.39% 33
2020
Q4 		$9.15M Hold
800,000
– – 0.49% 31
2020
Q3 		$8.29M Buy
+800,000
New +$8.17M 0.59% 24

Other funds holding TNGX

FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
BCM
Boxer Capital Management San Diego, California $762M AUM 1,125.36% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
TGI
TRV GP IV Boston, Massachusetts $267M AUM 965.83% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

EcoR1 Capital's TNGX Position: Q4 2025 in Review

EcoR1 Capital sold out of Tango Therapeutics (TNGX) in Q4 2025, closing a stake of 10,630,736 shares — an estimated $89.3M sold.

EcoR1 Capital first reported a position in TNGX in Q3 2020 and held it in 21 quarters. The position peaked at $132M in Q4 2023. 170 funds tracked by Wall St. Rank hold TNGX as of Q4 2025.

  • EcoR1 Capital reported no remaining Tango Therapeutics position as of Q4 2025 after selling out during the quarter.
  • EcoR1 Capital sold 10,630,736 Tango Therapeutics shares in Q4 2025, an estimated $89.3M.
  • EcoR1 Capital first reported a position in Tango Therapeutics in Q3 2020 and held it in 21 quarters.
  • EcoR1 Capital's Tango Therapeutics position peaked at $132M in Q4 2023.
  • 170 funds tracked by Wall St. Rank held Tango Therapeutics as of Q4 2025.

Based on EcoR1 Capital's 13F filing for Q4 2025, filed 17 Feb 2026.