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Small Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
RGNX icon
101
Regenxbio
RGNX
$623M
$623M $9.73 5.07%
CRMD icon
102
CorMedix
CRMD
$617M
$617M $7.87 2.24%
AGMB
103
AgomAb Therapeutics NV
AGMB
$616M
$616M $12.51 3.55%
NVCT icon
104
Nuvectis Pharma
NVCT
$609M
$609M $19.31 4.17%
IMMX icon
105
Immix Biopharma
IMMX
$607M
$607M $8.52 3.18%
CBIO
106
Crescent Biopharma
CBIO
$602M
$602M $16.30 4.29%
ALLO icon
107
Allogene Therapeutics
ALLO
$601M
$601M $1.74 4.4%
SPRY icon
108
ARS Pharmaceuticals
SPRY
$590M
$590M $5.94 1%
TECX
109
Tectonic Therapeutic
TECX
$573M
$573M $30.37 3.92%
ZVRA icon
110
Zevra Therapeutics
ZVRA
$563M
$563M $9.53 23.9%
RLMD icon
111
Relmada Therapeutics
RLMD
$544M
$544M $5.18 0.38%
ALT icon
112
Altimmune
ALT
$539M
$539M $2.77 2.46%
PRME icon
113
Prime Medicine
PRME
$533M
$533M $2.95 0.67%
VSTM icon
114
Verastem
VSTM
$532M
$532M $6.05 2.1%
FDMT icon
115
4D Molecular Therapeutics
FDMT
$526M
$526M $10.07 2.99%
CTNM
116
Contineum Therapeutics
CTNM
$526M
$526M $14.06 2.16%
SLN
117
Silence Therapeutics
SLN
$521M
$521M $11.02 3.76%
ARVN icon
118
Arvinas
ARVN
$518M
$518M $8.03 1.11%
ASMB icon
119
Assembly Biosciences
ASMB
$506M
$506M $25.55 1.31%
ZURA icon
120
Zura Bio
ZURA
$497M
$497M $5.23 1.13%
VALN
121
Valneva
VALN
$488M
$488M $4.78 0%
ARTV
122
Artiva Biotherapeutics
ARTV
$487M
$487M $10.03 0.99%
EIKN
123
Eikon Therapeutics
EIKN
$482M
$482M $8.90 7.48%
DNA icon
124
Ginkgo Bioworks
DNA
$481M
$481M $7.36 7.19%
RZLT icon
125
Rezolute
RZLT
$480M
$480M $4.99 6.03%
3 4
5
6 7

Small Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 180 small cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $250M and $2B — worth a combined $157B.

The largest by market cap are UroGen Pharma (URGN) at $2B, Mesoblast (MESO) at $1.99B and Palvella Therapeutics (PVLA) at $1.98B.

Among institutional investors, Aktis Oncology (AKTS) drew the most net new fund positions in Q1 2026: 69 funds opened new positions.

  • Combined market cap: $157B across 180 stocks.
  • Small Cap: market cap between $250M and $2B.
  • Largest constituent: UroGen Pharma (URGN), $2B market cap.
  • Most net new fund positions in Q1 2026: Aktis Oncology (AKTS), +69 holders.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q1 2026.