We are live on ! Find out more

Small Cap Biotechnology
Stocks Ranked by
Market Capitalization

Small Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 180 small cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $250M and $2B — worth a combined $157B.

The largest by market cap are UroGen Pharma (URGN) at $2B, Mesoblast (MESO) at $1.99B and Palvella Therapeutics (PVLA) at $1.98B.

Among institutional investors, Aktis Oncology (AKTS) drew the most net new fund positions in Q1 2026: 69 funds opened new positions.

  • Combined market cap: $157B across 180 stocks.
  • Small Cap: market cap between $250M and $2B.
  • Largest constituent: UroGen Pharma (URGN), $2B market cap.
  • Most net new fund positions in Q1 2026: Aktis Oncology (AKTS), +69 holders.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q1 2026.