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Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
KYMR icon
1
Kymera Therapeutics
KYMR
$9.6B
$9.6B $115.47 5.4%
ARWR icon
2
Arrowhead Research
ARWR
$9.46B
$9.46B $66.96 6.82%
CYTK icon
3
Cytokinetics
CYTK
$9.15B
$9.15B $65.81 2.63%
IBRX icon
4
ImmunityBio
IBRX
$9.15B
$9.15B $8.63 7.1%
PTGX icon
5
Protagonist Therapeutics
PTGX
$8.98B
$8.98B $138.70 4.39%
CAI
6
Caris Life Sciences
CAI
$8.94B
$8.94B $31.65 0.57%
TGTX icon
7
TG Therapeutics
TGTX
$8.57B
$8.57B $56 3.63%
PCVX icon
8
Vaxcyte
PCVX
$8.41B
$8.41B $56.49 4.29%
ABVX
9
Abivax
ABVX
$8.21B
$8.21B $94.13 4.23%
PRAX icon
10
Praxis Precision Medicines
PRAX
$7.88B
$7.88B $282.12 6.16%
SYRE icon
11
Spyre Therapeutics
SYRE
$7.77B
$7.77B $88.17 4.13%
IONS icon
12
Ionis Pharmaceuticals
IONS
$7.3B
$7.3B $43.93 3.98%
IMVT icon
13
Immunovant
IMVT
$7.13B
$7.13B $34.54 7.37%
BLTE
14
Belite Bio
BLTE
$6.79B
$6.79B $168.67 3.81%
RYTM icon
15
Rhythm Pharmaceuticals
RYTM
$6.76B
$6.76B $98.24 1.04%
CGON icon
16
CG Oncology
CGON
$6.5B
$6.5B $73.36 5.63%
SRRK icon
17
Scholar Rock
SRRK
$6.07B
$6.07B $49.85 2.62%
ORKA
18
Oruka Therapeutics
ORKA
$5.95B
$5.95B $89.92 4.9%
LGND icon
19
Ligand Pharmaceuticals
LGND
$5.95B
$5.95B $298.41 0.03%
MIRM icon
20
Mirum Pharmaceuticals
MIRM
$5.8B
$5.8B $89.32 2.27%
TVTX icon
21
Travere Therapeutics
TVTX
$5.64B
$5.64B $59.83 0.75%
COGT icon
22
Cogent Biosciences
COGT
$5.45B
$5.45B $31.41 3.74%
CRSP icon
23
CRISPR Therapeutics
CRSP
$5.39B
$5.39B $55.76 5.54%
DNTH icon
24
Dianthus Therapeutics
DNTH
$5.23B
$5.23B $93.44 4.99%
PTCT icon
25
PTC Therapeutics
PTCT
$5.2B
$5.2B $62.34 5.49%
1
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Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 76 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $338B.

The largest by market cap are Kymera Therapeutics (KYMR) at $9.6B, Arrowhead Research (ARWR) at $9.46B and Cytokinetics (CYTK) at $9.15B.

Among institutional investors, Definium Therapeutics (DFTX) drew the most net new fund positions in Q2 2026: 148 funds opened new positions, taking total fund holders up 114 (46%) quarter-over-quarter.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.