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Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
ORKA icon
26
Oruka Therapeutics
ORKA
$5.24B
$5.24B $79.09 6.19%
ERAS icon
27
Erasca
ERAS
$5.11B
$5.11B $14.62 7.34%
SRRK icon
28
Scholar Rock
SRRK
$5.04B
$5.04B $41.36 2.78%
TVTX icon
29
Travere Therapeutics
TVTX
$4.93B
$4.93B $52.30 3.58%
CRSP icon
30
CRISPR Therapeutics
CRSP
$4.82B
$4.82B $49.88 0.32%
DFTX icon
31
Definium Therapeutics
DFTX
$4.71B
$4.71B $35.09 6.43%
DNTH icon
32
Dianthus Therapeutics
DNTH
$4.4B
$4.4B $78.75 5.65%
EWTX icon
33
Edgewise Therapeutics
EWTX
$4.32B
$4.32B $39.75 4.83%
TNGX icon
34
Tango Therapeutics
TNGX
$4.26B
$4.26B $25.25 7.31%
ARQT icon
35
Arcutis Biotherapeutics
ARQT
$4.13B
$4.13B $32.82 2.92%
RLAY icon
36
Relay Therapeutics
RLAY
$4.04B
$4.04B $18.45 7.96%
ABCL icon
37
AbCellera Biologics
ABCL
$3.79B
$3.79B $11.71 1.84%
TLX icon
38
Telix Pharmaceuticals
TLX
$3.79B
$3.79B $11.16 3.91%
LEGN icon
39
Legend Biotech
LEGN
$3.7B
$3.7B $19.01 1.93%
ACAD icon
40
Acadia Pharmaceuticals
ACAD
$3.52B
$3.52B $20.44 3.23%
XENE icon
41
Xenon Pharmaceuticals
XENE
$3.51B
$3.51B $36.27 3.39%
IDYA icon
42
IDEAYA Biosciences
IDYA
$3.41B
$3.41B $35.36 4.58%
VKTX icon
43
Viking Therapeutics
VKTX
$3.4B
$3.4B $26.71 6.63%
PBLS
44
Parabilis Medicines Inc
PBLS
$3.35B
$3.35B $27.08 6.82%
TARS icon
45
Tarsus Pharmaceuticals
TARS
$3.32B
$3.32B $71.03 2.2%
IRON icon
46
Disc Medicine
IRON
$3.05B
$3.05B $79.48 0.7%
DYN icon
47
Dyne Therapeutics
DYN
$3.04B
$3.04B $16.27 6.83%
DNLI icon
48
Denali Therapeutics
DNLI
$3.03B
$3.03B $18.93 4.93%
RCUS icon
49
Arcus Biosciences
RCUS
$3.02B
$3.02B $23.75 7.27%
ELVN icon
50
Enliven Therapeutics
ELVN
$3.02B
$3.02B $41.25 6.59%
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Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 71 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $333B.

The largest by market cap are Krystal Biotech (KRYS) at $9.6B, Twist Bioscience (TWST) at $9.46B and Kymera Therapeutics (KYMR) at $9.43B.

Among institutional investors, Definium Therapeutics (DFTX) drew the most net new fund positions in Q2 2026: 149 funds opened new positions, taking total fund holders up 115 (46%) quarter-over-quarter.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.