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Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
CRSP icon
26
CRISPR Therapeutics
CRSP
$4.68B
$4.68B $47.55 1.75%
MANE
27
Veradermics Inc
MANE
$4.66B
$4.66B $111.54 0.11%
ACAD icon
28
Acadia Pharmaceuticals
ACAD
$4.45B
$4.45B $26.01 2.44%
CAI
29
Caris Life Sciences
CAI
$4.41B
$4.41B $15.59 0.26%
EWTX icon
30
Edgewise Therapeutics
EWTX
$4.34B
$4.34B $40.35 3%
TNGX icon
31
Tango Therapeutics
TNGX
$4.34B
$4.34B $26.65 0.26%
DYN icon
32
Dyne Therapeutics
DYN
$4.28B
$4.28B $25.90 1.05%
CELC icon
33
Celcuity
CELC
$4.02B
$4.02B $82.46 0.23%
RLAY icon
34
Relay Therapeutics
RLAY
$3.99B
$3.99B $18.29 1.88%
VKTX icon
35
Viking Therapeutics
VKTX
$3.93B
$3.93B $33.86 2.9%
PBLS
36
Parabilis Medicines Inc
PBLS
$3.91B
$3.91B $31.96 0.44%
ELVN icon
37
Enliven Therapeutics
ELVN
$3.84B
$3.84B $53.76 1.93%
DNLI icon
38
Denali Therapeutics
DNLI
$3.82B
$3.82B $24.05 2.04%
LEGN icon
39
Legend Biotech
LEGN
$3.68B
$3.68B $19.04 1.19%
ARQT icon
40
Arcutis Biotherapeutics
ARQT
$3.55B
$3.55B $28.42 2.08%
IDYA icon
41
IDEAYA Biosciences
IDYA
$3.48B
$3.48B $36.16 1.66%
TLX
42
Telix Pharmaceuticals
TLX
$3.45B
$3.45B $10.19 2.1%
ALMS
43
Alumis Inc
ALMS
$3.45B
$3.45B $27.03 0.18%
GPCR icon
44
Structure Therapeutics
GPCR
$3.4B
$3.4B $47.89 1.64%
RCUS icon
45
Arcus Biosciences
RCUS
$3.4B
$3.4B $27.05 2.84%
NAMS icon
46
NewAmsterdam Pharma
NAMS
$3.27B
$3.27B $27.98 7.41%
MBX
47
MBX Biosciences
MBX
$2.86B
$2.86B $60.06 2.02%
IRON icon
48
Disc Medicine
IRON
$2.85B
$2.85B $74.65 0.05%
CLDX icon
49
Celldex Therapeutics
CLDX
$2.79B
$2.79B $35.58 0.2%
BEAM icon
50
Beam Therapeutics
BEAM
$2.7B
$2.7B $26.29 4.87%
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Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 77 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $336B.

The largest by market cap are Halozyme (HALO) at $9.9B, Ionis Pharmaceuticals (IONS) at $9.14B and Crinetics Pharmaceuticals (CRNX) at $8.88B.

Among institutional investors, ImmunityBio (IBRX) drew the most net new fund positions in Q1 2026: 145 funds opened new positions, taking total fund holders up 110 (40%) quarter-over-quarter.

  • Combined market cap: $336B across 77 stocks.
  • Mid Cap: market cap between $2B and $10B.
  • Largest constituent: Halozyme (HALO), $9.9B market cap.
  • Most net new fund positions in Q1 2026: ImmunityBio (IBRX), +110 holders.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q1 2026.