We are live on ! Find out more

Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
PBLS
26
Parabilis Medicines Inc
PBLS
$4.85B
$4.85B $39.23 2.08%
EWTX icon
27
Edgewise Therapeutics
EWTX
$4.8B
$4.8B $44.21 1.14%
CELC icon
28
Celcuity
CELC
$4.51B
$4.51B $92.27 1.63%
RLAY icon
29
Relay Therapeutics
RLAY
$4.51B
$4.51B $20.57 4.1%
ELVN icon
30
Enliven Therapeutics
ELVN
$4.47B
$4.47B $61.01 0.23%
MANE
31
Veradermics Inc
MANE
$4.28B
$4.28B $102.35 3.95%
TNGX icon
32
Tango Therapeutics
TNGX
$4.18B
$4.18B $24.77 1.06%
LEGN icon
33
Legend Biotech
LEGN
$4.14B
$4.14B $21.30 1.72%
IDYA icon
34
IDEAYA Biosciences
IDYA
$4.1B
$4.1B $42.48 6.09%
ABCL icon
35
AbCellera Biologics
ABCL
$4.05B
$4.05B $12.50 17.8%
RCUS icon
36
Arcus Biosciences
RCUS
$4.02B
$4.02B $31.57 4.81%
VKTX icon
37
Viking Therapeutics
VKTX
$3.99B
$3.99B $34.17 2.83%
DNLI icon
38
Denali Therapeutics
DNLI
$3.98B
$3.98B $24.93 3.02%
TLX
39
Telix Pharmaceuticals
TLX
$3.96B
$3.96B $11.69 0.09%
IOVA icon
40
Iovance Biotherapeutics
IOVA
$3.82B
$3.82B $8.44 4.71%
GPCR icon
41
Structure Therapeutics
GPCR
$3.56B
$3.56B $49.92 1.86%
QURE icon
42
uniQure
QURE
$3.54B
$3.54B $51.05 7.56%
IMNM icon
43
Immunome
IMNM
$3.34B
$3.34B $29.39 4.93%
MBX
44
MBX Biosciences
MBX
$3.3B
$3.3B $68.62 3.36%
NAMS icon
45
NewAmsterdam Pharma
NAMS
$3.27B
$3.27B $27.34 1.82%
CLDX icon
46
Celldex Therapeutics
CLDX
$3.24B
$3.24B $41.22 1.6%
BEAM icon
47
Beam Therapeutics
BEAM
$3.21B
$3.21B $31.03 9.53%
IRON icon
48
Disc Medicine
IRON
$3.16B
$3.16B $82.41 1.82%
TARS icon
49
Tarsus Pharmaceuticals
TARS
$3.14B
$3.14B $71.45 1.87%
ARQT icon
50
Arcutis Biotherapeutics
ARQT
$3.12B
$3.12B $24.86 0.32%
1
2
3 4

Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 84 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $356B.

The largest by market cap are Protagonist Therapeutics (PTGX) at $9.74B, Spyre Therapeutics (SYRE) at $9.47B and Vaxcyte (PCVX) at $9.09B.

Among institutional investors, Definium Therapeutics (DFTX) drew the most net new fund positions in Q2 2026: 148 funds opened new positions, taking total fund holders up 114 (46%) quarter-over-quarter.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.