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Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
MANE
26
Veradermics Inc
MANE
$4.94B
$4.94B $118.14 4.73%
EWTX icon
27
Edgewise Therapeutics
EWTX
$4.83B
$4.83B $44.51 0.29%
IOVA icon
28
Iovance Biotherapeutics
IOVA
$4.82B
$4.82B $10.64 4.42%
VKTX icon
29
Viking Therapeutics
VKTX
$4.77B
$4.77B $40.85 35.7%
PBLS
30
Parabilis Medicines Inc
PBLS
$4.72B
$4.72B $38.17 3.36%
ACAD icon
31
Acadia Pharmaceuticals
ACAD
$4.55B
$4.55B $26.41 0.04%
TNGX icon
32
Tango Therapeutics
TNGX
$4.3B
$4.3B $25.53 14.3%
RLAY icon
33
Relay Therapeutics
RLAY
$4.24B
$4.24B $19.35 6.38%
CELC icon
34
Celcuity
CELC
$4.12B
$4.12B $84.10 0.12%
ABCL icon
35
AbCellera Biologics
ABCL
$4.1B
$4.1B $12.65 0.08%
TLX
36
Telix Pharmaceuticals
TLX
$4.06B
$4.06B $11.95 5.66%
IDYA icon
37
IDEAYA Biosciences
IDYA
$3.83B
$3.83B $39.71 2.19%
XENE icon
38
Xenon Pharmaceuticals
XENE
$3.79B
$3.79B $39.09 0.26%
LEGN icon
39
Legend Biotech
LEGN
$3.63B
$3.63B $18.64 0.59%
TARS icon
40
Tarsus Pharmaceuticals
TARS
$3.61B
$3.61B $77.08 0.49%
ELVN icon
41
Enliven Therapeutics
ELVN
$3.53B
$3.53B $48.19 1.39%
ARQT icon
42
Arcutis Biotherapeutics
ARQT
$3.49B
$3.49B $27.78 7.01%
DNLI icon
43
Denali Therapeutics
DNLI
$3.45B
$3.45B $21.60 5.52%
RCUS icon
44
Arcus Biosciences
RCUS
$3.42B
$3.42B $26.87 3.55%
DYN icon
45
Dyne Therapeutics
DYN
$3.2B
$3.2B $17.14 0.12%
QURE icon
46
uniQure
QURE
$3.14B
$3.14B $45.28 2.19%
MBX
47
MBX Biosciences
MBX
$2.98B
$2.98B $61.98 1.71%
ZLAB icon
48
Zai Lab
ZLAB
$2.96B
$2.96B $26.41 0.08%
IMNM icon
49
Immunome
IMNM
$2.92B
$2.92B $25.75 2.71%
PGEN icon
50
Precigen
PGEN
$2.82B
$2.82B $7.89 2.47%
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Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 80 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $346B.

The largest by market cap are ImmunityBio (IBRX) at $9.85B, Cytokinetics (CYTK) at $9.4B and Protagonist Therapeutics (PTGX) at $9.39B.

Among institutional investors, Definium Therapeutics (DFTX) drew the most net new fund positions in Q2 2026: 148 funds opened new positions, taking total fund holders up 114 (46%) quarter-over-quarter.

  • Combined market cap: $346B across 80 stocks.
  • Mid Cap: market cap between $2B and $10B.
  • Largest constituent: ImmunityBio (IBRX), $9.85B market cap.
  • Most net new fund positions in Q2 2026: Definium Therapeutics (DFTX), +114 holders.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.