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Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
SRRK icon
26
Scholar Rock
SRRK
$5.17B
$5.17B $42.45 2.19%
MIRM icon
27
Mirum Pharmaceuticals
MIRM
$5.15B
$5.15B $79.25 2.68%
ERAS icon
28
Erasca
ERAS
$5B
$5B $14.30 2.85%
DFTX
29
Definium Therapeutics
DFTX
$4.79B
$4.79B $35.62 1.68%
DNTH icon
30
Dianthus Therapeutics
DNTH
$4.78B
$4.78B $85.40 3%
MANE
31
Veradermics Inc
MANE
$4.55B
$4.55B $108.96 8.34%
EWTX icon
32
Edgewise Therapeutics
EWTX
$4.35B
$4.35B $40.02 0.69%
ABCL icon
33
AbCellera Biologics
ABCL
$4.26B
$4.26B $13.15 4.57%
RLAY icon
34
Relay Therapeutics
RLAY
$4.11B
$4.11B $18.74 3.35%
TNGX icon
35
Tango Therapeutics
TNGX
$3.69B
$3.69B $21.90 5.11%
TLX
36
Telix Pharmaceuticals
TLX
$3.66B
$3.66B $10.78 0.92%
LEGN icon
37
Legend Biotech
LEGN
$3.64B
$3.64B $18.72 0.32%
VKTX icon
38
Viking Therapeutics
VKTX
$3.61B
$3.61B $28.38 3.07%
PBLS
39
Parabilis Medicines Inc
PBLS
$3.57B
$3.57B $28.86 2.27%
XENE icon
40
Xenon Pharmaceuticals
XENE
$3.54B
$3.54B $36.57 2.66%
IDYA icon
41
IDEAYA Biosciences
IDYA
$3.53B
$3.53B $36.63 3.76%
CELC icon
42
Celcuity
CELC
$3.49B
$3.49B $71.25 3.22%
TARS icon
43
Tarsus Pharmaceuticals
TARS
$3.47B
$3.47B $74.11 0.47%
ACAD icon
44
Acadia Pharmaceuticals
ACAD
$3.4B
$3.4B $19.74 1.84%
ELVN icon
45
Enliven Therapeutics
ELVN
$3.11B
$3.11B $42.39 6.77%
RCUS icon
46
Arcus Biosciences
RCUS
$3.09B
$3.09B $24.28 1.86%
DNLI icon
47
Denali Therapeutics
DNLI
$3.08B
$3.08B $19.28 3.16%
ARQT icon
48
Arcutis Biotherapeutics
ARQT
$3.01B
$3.01B $23.92 4.89%
DYN icon
49
Dyne Therapeutics
DYN
$2.88B
$2.88B $15.40 0.26%
ZLAB icon
50
Zai Lab
ZLAB
$2.87B
$2.87B $25.58 0.16%
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Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 68 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $316B.

The largest by market cap are Vaxcyte (PCVX) at $9.93B, Krystal Biotech (KRYS) at $9.67B and Axsome Therapeutics (AXSM) at $9.13B.

Among institutional investors, Definium Therapeutics (DFTX) drew the most net new fund positions in Q2 2026: 148 funds opened new positions, taking total fund holders up 114 (46%) quarter-over-quarter.

  • Combined market cap: $316B across 68 stocks.
  • Mid Cap: market cap between $2B and $10B.
  • Largest constituent: Vaxcyte (PCVX), $9.93B market cap.
  • Most net new fund positions in Q2 2026: Definium Therapeutics (DFTX), +114 holders.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.