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Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
MANE icon
26
Veradermics Inc
MANE
$5.58B
$5.58B $133.61 3.15%
COGT icon
27
Cogent Biosciences
COGT
$5.39B
$5.39B $31.06 4.47%
SRRK icon
28
Scholar Rock
SRRK
$5.36B
$5.36B $43.98 2.49%
ERAS icon
29
Erasca
ERAS
$5.12B
$5.12B $14.64 4.2%
CRSP icon
30
CRISPR Therapeutics
CRSP
$4.83B
$4.83B $49.99 0%
TVTX icon
31
Travere Therapeutics
TVTX
$4.66B
$4.66B $49.41 0.3%
DNTH icon
32
Dianthus Therapeutics
DNTH
$4.63B
$4.63B $82.70 0.55%
DFTX icon
33
Definium Therapeutics
DFTX
$4.49B
$4.49B $33.41 2.89%
LEGN icon
34
Legend Biotech
LEGN
$4.18B
$4.18B $21.48 1.8%
EWTX icon
35
Edgewise Therapeutics
EWTX
$4.09B
$4.09B $37.68 1.13%
ARQT icon
36
Arcutis Biotherapeutics
ARQT
$4.02B
$4.02B $32 2.37%
IOVA icon
37
Iovance Biotherapeutics
IOVA
$4B
$4B $8.83 10.1%
ABCL icon
38
AbCellera Biologics
ABCL
$3.95B
$3.95B $12.18 9.53%
TNGX icon
39
Tango Therapeutics
TNGX
$3.91B
$3.91B $23.17 6.48%
RLAY icon
40
Relay Therapeutics
RLAY
$3.82B
$3.82B $17.44 0.93%
XENE icon
41
Xenon Pharmaceuticals
XENE
$3.7B
$3.7B $38.23 1.62%
PBLS
42
Parabilis Medicines Inc
PBLS
$3.61B
$3.61B $29.25 7.34%
IRON icon
43
Disc Medicine
IRON
$3.6B
$3.6B $81.16 3.23%
ACAD icon
44
Acadia Pharmaceuticals
ACAD
$3.54B
$3.54B $20.57 0.49%
CELC icon
45
Celcuity
CELC
$3.41B
$3.41B $69.72 3.95%
TARS icon
46
Tarsus Pharmaceuticals
TARS
$3.4B
$3.4B $72.64 0.93%
DYN icon
47
Dyne Therapeutics
DYN
$3.37B
$3.37B $18.05 4.34%
VKTX icon
48
Viking Therapeutics
VKTX
$3.33B
$3.33B $26.09 2.76%
ELVN icon
49
Enliven Therapeutics
ELVN
$3.28B
$3.28B $44.83 0.45%
DNLI icon
50
Denali Therapeutics
DNLI
$3.11B
$3.11B $19.45 3.13%
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Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 76 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $357B.

The largest by market cap are Vaxcyte (PCVX) at $9.6B, Twist Bioscience (TWST) at $9.3B and TG Therapeutics (TGTX) at $9.3B.

Among institutional investors, Definium Therapeutics (DFTX) drew the most net new fund positions in Q2 2026: 149 funds opened new positions, taking total fund holders up 114 (46%) quarter-over-quarter.

  • Combined market cap: $357B across 76 stocks.
  • Mid Cap: market cap between $2B and $10B.
  • Largest constituent: Vaxcyte (PCVX), $9.6B market cap.
  • Most net new fund positions in Q2 2026: Definium Therapeutics (DFTX), +114 holders.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.