CRISPR Therapeutics
CRSP
About: Crispr Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for clustered regularly interspaced short palindromic repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. Crispr's first approved drug is Casgevy, which was developed in collaboration with Vertex Pharmaceuticals and targets sickle-cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is advancing a variety of gene editing programs in immuno-oncology, cardiovascular, and a stem cell-derived therapy to treat Type 1 diabetes.
Employees: 393
Fund manager confidence
Based on 2025 Q2 regulatory disclosures by fund managers ($100M+ AUM)
74% more first-time investments, than exits
New positions opened: 101 | Existing positions closed: 58
61% more capital invested
Capital invested by funds: $2.19B [Q1] → $3.52B (+$1.33B) [Q2]
31% more call options, than puts
Call options by funds: $244M | Put options by funds: $186M
24% more repeat investments, than reductions
Existing positions increased: 124 | Existing positions reduced: 100
10% more funds holding
Funds holding: 387 [Q1] → 424 (+37) [Q2]
8.95% more ownership
Funds ownership: 74.81% [Q1] → 83.77% (+8.95%) [Q2]
0% more funds holding in top 10
Funds holding in top 10: 6 [Q1] → 6 (+0) [Q2]
Research analyst outlook
9 Wall Street Analysts provided 1 year price targets over the past 3 months
9 analyst ratings
HC Wainwright & Co.
Mitchell Kapoor
|
$80
|
Buy
Maintained
|
7 Aug 2025 |
Barclays
Gena Wang
|
$56
|
Equal-Weight
Maintained
|
6 Aug 2025 |
Chardan Capital
Geulah Livshits
|
$82
|
Buy
Maintained
|
5 Aug 2025 |
RBC Capital
Luca Issi
|
$42
|
Sector Perform
Maintained
|
5 Aug 2025 |
B of A Securities
Geoff Meacham
|
$78
|
Buy
Maintained
|
22 Jul 2025 |
Needham
Gil Blum
|
$81
|
Buy
Reiterated
|
8 Jul 2025 |
Clear Street
Bill Maughan
|
$45
|
Hold
Downgraded
|
27 Jun 2025 |
Piper Sandler
Edward Tenthoff
|
$105
|
Overweight
Reiterated
|
27 Jun 2025 |
JMP Securities
Silvan Tuerkcan
|
$86
|
Market Outperform
Reiterated
|
27 Jun 2025 |
Financial journalist opinion
Based on 18 articles about CRSP published over the past 30 days