|
1
|
ARK Investment Management
St. Petersburg,
Florida
|
$516M
|
-$97.7M
|
-1,852,684
|
-16%
|
|
|
2
|
|
$455M
|
+$35.3M
|
+668,904
|
+9%
|
|
|
3
|
Orbis Allan Gray
Hamilton,
Bermuda
|
$297M
|
-$34.6M
|
-656,850
|
-11%
|
|
|
4
|
Capital World Investors
Los Angeles,
California
|
$259M
|
+$1.29M
|
+24,488
|
+0.5%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$236M
|
+$17.9M
|
+339,166
|
+9%
|
|
|
6
|
|
$176M
|
–
|
–
|
–
|
|
|
7
|
Geode Capital Management
Boston,
Massachusetts
|
$137M
|
+$7M
|
+132,751
|
+6%
|
|
|
8
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$112M
|
-$47.4M
|
-899,578
|
-30%
|
|
|
9
|
SR One Capital Management
Wayne,
Pennsylvania
|
$111M
|
–
|
–
|
–
|
|
|
10
|
Two Sigma Investments
New York
|
$108M
|
+$26.6M
|
+505,570
|
+34%
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
$104M
|
-$2.43M
|
-46,191
|
-2%
|
|
|
12
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$93.8M
|
-$7.02M
|
-133,141
|
-7%
|
|
|
13
|
Nikko Asset Management Americas
New York
|
$93.8M
|
-$7.05M
|
-133,778
|
-7%
|
|
|
14
|
EcoR1 Capital
San Francisco,
California
|
$75.8M
|
–
|
–
|
–
|
|
|
15
|
UBS Group
Zurich,
Switzerland
|
$71.9M
|
-$23.5M
|
-445,031
|
-25%
|
|
|
16
|
Capital International Investors
Los Angeles,
California
|
$69.2M
|
+$4.3M
|
+81,613
|
+7%
|
|
|
17
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$64.5M
|
+$2.07M
|
+39,304
|
+3%
|
|
|
18
|
Bank of America
Charlotte,
North Carolina
|
$63M
|
+$9.07M
|
+172,033
|
+17%
|
|
|
19
|
NEA Management Company
Timonium,
Maryland
|
$57.7M
|
–
|
–
|
–
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$57.7M
|
+$974K
|
+18,488
|
+2%
|
|
|
21
|
|
$48.7M
|
+$47.1M
|
+893,812
|
New
|
|
|
22
|
|
$48M
|
+$11.2M
|
+211,807
|
+32%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$47.1M
|
+$3.21M
|
+60,910
|
+8%
|
|
|
24
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$35.4M
|
+$5.37M
|
+101,887
|
+19%
|
|
|
25
|
Vanguard Fiduciary Trust
Malvern,
Pennsylvania
|
$31.1M
|
+$1.44M
|
+27,358
|
+5%
|
|
