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Small Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
MESO icon
1
Mesoblast
MESO
$1.97B
$1.97B $15.16 3.25%
SRPT icon
2
Sarepta Therapeutics
SRPT
$1.97B
$1.97B $18.62 3.17%
SLS icon
3
SELLAS Life Sciences
SLS
$1.95B
$1.95B $9.68 4.72%
BRVE
4
Braveheart Bio
BRVE
$1.94B
$1.94B $21.51 1.51%
COAG icon
5
Hemab Therapeutics
COAG
$1.94B
$1.94B $41.45 2.55%
TRVI icon
6
Trevi Therapeutics
TRVI
$1.93B
$1.93B $13.56 1.81%
VIR icon
7
Vir Biotechnology
VIR
$1.91B
$1.91B $11.30 3.83%
ABSI icon
8
Absci
ABSI
$1.91B
$1.91B $11.13 8.02%
TRAX icon
9
First Tracks Biotherapeutics
TRAX
$1.89B
$1.89B $45.08 0.33%
GENB icon
10
Generate Biomedicines
GENB
$1.86B
$1.86B $14.46 8.31%
ZBIO icon
11
Zenas BioPharma
ZBIO
$1.85B
$1.85B $28.39 1.29%
AGIO icon
12
Agios Pharmaceuticals
AGIO
$1.82B
$1.82B $30.55 17.9%
ADRX icon
13
ADARx Pharmaceuticals, Inc. Common Stock
ADRX
$1.82B
$1.82B $17 4.76%
MAZE icon
14
Maze Therapeutics
MAZE
$1.75B
$1.75B $31.48 1.41%
NTLA icon
15
Intellia Therapeutics
NTLA
$1.75B
$1.75B $12.47 5.74%
QURE icon
16
uniQure
QURE
$1.72B
$1.72B $24.83 1.86%
STOK icon
17
Stoke Therapeutics
STOK
$1.7B
$1.7B $26.29 0.23%
NUVB icon
18
Nuvation Bio
NUVB
$1.67B
$1.67B $4.76 0.21%
REPL icon
19
Replimune Group
REPL
$1.67B
$1.67B $17.61 1.27%
KLRA icon
20
Kailera Therapeutics
KLRA
$1.67B
$1.67B $12.86 4.1%
NVAX icon
21
Novavax
NVAX
$1.66B
$1.66B $10.08 3.72%
MLYS icon
22
Mineralys Therapeutics
MLYS
$1.61B
$1.61B $18.18 14.4%
URGN icon
23
UroGen Pharma
URGN
$1.6B
$1.6B $32.72 2.27%
NBTX icon
24
Nanobiotix
NBTX
$1.6B
$1.6B $31.37 7.19%
RARE icon
25
Ultragenyx Pharmaceutical
RARE
$1.59B
$1.59B $16.10 4.05%
1
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Small Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 180 small cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $250M and $2B — worth a combined $151B.

The largest by market cap are Mesoblast (MESO) at $1.97B, Sarepta Therapeutics (SRPT) at $1.97B and SELLAS Life Sciences (SLS) at $1.95B.

Among institutional investors, First Tracks Biotherapeutics (TRAX) drew the most net new fund positions in Q2 2026: 150 funds opened new positions.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.