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Small Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
NBTX
1
Nanobiotix
NBTX
$1.94B
$1.94B $38.22 1.14%
AGIO icon
2
Agios Pharmaceuticals
AGIO
$1.93B
$1.93B $32.27 1%
TSHA icon
3
Taysha Gene Therapies
TSHA
$1.89B
$1.89B $6.56 3.47%
BCAX
4
Bicara Therapeutics
BCAX
$1.84B
$1.84B $28.06 2%
GENB
5
Generate Biomedicines
GENB
$1.84B
$1.84B $14.35 3.31%
DMRA
6
Damora Therapeutics, Inc. Ordinary Shares
DMRA
$1.84B
$1.84B $29.92 0.13%
KARD
7
Kardigan Inc
KARD
$1.83B
$1.83B $20.50 0.69%
SNDX icon
8
Syndax Pharmaceuticals
SNDX
$1.82B
$1.82B $20.40 3.24%
SRPT icon
9
Sarepta Therapeutics
SRPT
$1.77B
$1.77B $16.78 0%
AAPG
10
Ascentage Pharma
AAPG
$1.77B
$1.77B $18.98 11.1%
LKFT
11
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.77B
$1.77B $27 3.33%
FTRE icon
12
Fortrea Holdings
FTRE
$1.75B
$1.75B $18.43 4.18%
SEPN
13
Septerna Inc
SEPN
$1.75B
$1.75B $38.83 1.77%
IMCR icon
14
Immunocore
IMCR
$1.73B
$1.73B $34 1.45%
RXRX icon
15
Recursion Pharmaceuticals
RXRX
$1.73B
$1.73B $3.22 1.26%
ANAB icon
16
AnaptysBio
ANAB
$1.68B
$1.68B $56.61 3.36%
ZYME icon
17
Zymeworks
ZYME
$1.67B
$1.67B $23.54 1.77%
NTLA icon
18
Intellia Therapeutics
NTLA
$1.67B
$1.67B $11.94 6.23%
MAZE
19
Maze Therapeutics
MAZE
$1.59B
$1.59B $28.65 0.42%
TYRA icon
20
Tyra Biosciences
TYRA
$1.58B
$1.58B $26.51 1.67%
TRAX
21
First Tracks Biotherapeutics
TRAX
$1.58B
$1.58B $45.33 0.04%
FBRX icon
22
Forte Biosciences
FBRX
$1.57B
$1.57B $76.79 0.05%
MLTX icon
23
MoonLake Immunotherapeutics
MLTX
$1.55B
$1.55B $18.26 1.28%
XNCR icon
24
Xencor
XNCR
$1.55B
$1.55B $20.81 4.05%
ABSI icon
25
Absci
ABSI
$1.51B
$1.51B $8.93 7.59%
1
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Small Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 181 small cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $250M and $2B — worth a combined $149B.

The largest by market cap are Nanobiotix (NBTX) at $1.94B, Agios Pharmaceuticals (AGIO) at $1.93B and Taysha Gene Therapies (TSHA) at $1.89B.

Among institutional investors, Aktis Oncology (AKTS) drew the most net new fund positions in Q1 2026: 69 funds opened new positions.

  • Combined market cap: $149B across 181 stocks.
  • Small Cap: market cap between $250M and $2B.
  • Largest constituent: Nanobiotix (NBTX), $1.94B market cap.
  • Most net new fund positions in Q1 2026: Aktis Oncology (AKTS), +69 holders.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q1 2026.