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Small Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
TRVI icon
1
Trevi Therapeutics
TRVI
$1.98B
$1.98B $13.91 1.9%
GPCR icon
2
Structure Therapeutics
GPCR
$1.97B
$1.97B $27.67 4.52%
ADRX
3
ADARx Pharmaceuticals, Inc. Common Stock
ADRX
$1.95B
$1.95B $18.25 6.6%
BHVN icon
4
Biohaven
BHVN
$1.94B
$1.94B $12.87 2.05%
LKFT
5
Lakefront Biotherapeutics American Depositary Shares
LKFT
$1.92B
$1.92B $29.37 1.77%
BRVE
6
Braveheart Bio
BRVE
$1.92B
$1.92B $21.27 0.65%
PVLA
7
Palvella Therapeutics
PVLA
$1.91B
$1.91B $132.47 0.2%
FTRE icon
8
Fortrea Holdings
FTRE
$1.9B
$1.9B $20 3.09%
ABSI icon
9
Absci
ABSI
$1.9B
$1.9B $11.07 2.98%
AGIO icon
10
Agios Pharmaceuticals
AGIO
$1.9B
$1.9B $31.80 2.09%
VIR icon
11
Vir Biotechnology
VIR
$1.89B
$1.89B $11.17 1.06%
SRPT icon
12
Sarepta Therapeutics
SRPT
$1.85B
$1.85B $17.50 0.4%
XNCR icon
13
Xencor
XNCR
$1.85B
$1.85B $24.84 0.28%
ZBIO
14
Zenas BioPharma
ZBIO
$1.84B
$1.84B $28.30 1.29%
MESO
15
Mesoblast
MESO
$1.83B
$1.83B $14.08 1.68%
NUVB icon
16
Nuvation Bio
NUVB
$1.8B
$1.8B $5.14 7.55%
ZYME icon
17
Zymeworks
ZYME
$1.8B
$1.8B $25.15 3.12%
SEPN
18
Septerna Inc
SEPN
$1.76B
$1.76B $37.71 0.89%
GENB
19
Generate Biomedicines
GENB
$1.76B
$1.76B $13.69 0.8%
NVAX icon
20
Novavax
NVAX
$1.73B
$1.73B $10.46 1.32%
NTLA icon
21
Intellia Therapeutics
NTLA
$1.72B
$1.72B $12.26 1.16%
STOK icon
22
Stoke Therapeutics
STOK
$1.65B
$1.65B $25.62 1.5%
QURE icon
23
uniQure
QURE
$1.63B
$1.63B $23.46 0.39%
GHRS icon
24
GH Research
GHRS
$1.57B
$1.57B $22.94 0.35%
SNDX icon
25
Syndax Pharmaceuticals
SNDX
$1.57B
$1.57B $17.60 3.4%
1
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Small Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 191 small cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $250M and $2B — worth a combined $164B.

The largest by market cap are Trevi Therapeutics (TRVI) at $1.98B, Structure Therapeutics (GPCR) at $1.97B and ADARx Pharmaceuticals, Inc. Common Stock (ADRX) at $1.95B.

Among institutional investors, First Tracks Biotherapeutics (TRAX) drew the most net new fund positions in Q2 2026: 150 funds opened new positions.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.