13.00 USD
+3.61
38.45%
At close Apr 17, 4:00 PM EDT
After hours
13.24
+0.24
1.85%
1 day
38.45%
5 days
51.16%
1 month
-10.53%
3 months
-7.47%
6 months
107.01%
Year to date
-27.98%
1 year
178.37%
5 years
-76.76%
10 years
-51.80%
 

About: uniQure NV is a gene therapy company. It develops treatments and platforms for patients suffering from genetic and other devastating diseases. Its products and services are focused on hemophilia, Huntington's disease, and cardiovascular diseases. The company is focused on the development of the pipeline of gene therapies with the collaboration of Bristol Myers Squibb for cardiovascular diseases.

Employees: 209

0
Funds holding %
of 7,407 funds
0
Analysts bullish %
of 4 analysts

Fund manager confidence

Based on 2024 Q4 regulatory disclosures by fund managers ($100M+ AUM)

292% more call options, than puts

Call options by funds: $51.5M | Put options by funds: $13.2M

281% more capital invested

Capital invested by funds: $193M [Q3] → $734M (+$541M) [Q4]

33% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 27

5.53% more ownership

Funds ownership: 79.83% [Q3] → 85.36% (+5.53%) [Q4]

5% more funds holding

Funds holding: 130 [Q3] → 137 (+7) [Q4]

23% less repeat investments, than reductions

Existing positions increased: 36 | Existing positions reduced: 47

Research analyst outlook

4 Wall Street Analysts provided 1 year price targets over the past 3 months

Low target
$24
85%
upside
Avg. target
$41
212%
upside
High target
$70
438%
upside

4 analyst ratings

positive
75%
neutral
25%
negative
0%
Chardan Capital
Daniil Gataulin
16% 1-year accuracy
8 / 49 met price target
192%upside
$38
Buy
Maintained
1 Apr 2025
HC Wainwright & Co.
Patrick Trucchio
15% 1-year accuracy
28 / 186 met price target
438%upside
$70
Buy
Reiterated
4 Mar 2025
Wells Fargo
Yanan Zhu
12% 1-year accuracy
2 / 17 met price target
131%upside
$30
Equal-Weight
Maintained
28 Feb 2025
RBC Capital
Luca Issi
7% 1-year accuracy
4 / 55 met price target
85%upside
$24
Outperform
Reiterated
21 Jan 2025

Financial journalist opinion

Positive
Benzinga
19 hours ago
Why Is Gene Therapy Developer uniQure Stock Trading Higher On Thursday?
The U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy designation to uniQure N.V.'s QURE AMT-130 for Huntington's disease on Thursday
Why Is Gene Therapy Developer uniQure Stock Trading Higher On Thursday?
Neutral
GlobeNewsWire
22 hours ago
uniQure Announces FDA Breakthrough Therapy Designation Granted to AMT-130 for the Treatment of Huntington's Disease
~ Breakthrough Therapy designation based on clinical evidence from Phase I/II trials showing meaningful slowing of disease progression ~
uniQure Announces FDA Breakthrough Therapy Designation Granted to AMT-130 for the Treatment of Huntington's Disease
Negative
Zacks Investment Research
1 month ago
UniQure (QURE) Reports Q4 Loss, Misses Revenue Estimates
UniQure (QURE) came out with a quarterly loss of $1.50 per share versus the Zacks Consensus Estimate of a loss of $0.44. This compares to loss of $1.53 per share a year ago.
UniQure (QURE) Reports Q4 Loss, Misses Revenue Estimates
Neutral
GlobeNewsWire
1 month ago
uniQure Announces 2024 Financial Results and Highlights Recent Company Progress
~ Announced alignment with the U.S. Food and Drug Administration (FDA) on key elements of the Accelerated Approval pathway for AMT-130 in Huntington's disease; Initiated preparations for a potential Biologics License Application (BLA) submission ~
uniQure Announces 2024 Financial Results and Highlights Recent Company Progress
Positive
Seeking Alpha
1 month ago
uniQure N.V.: A Potential Huntington's Play
uniQure's stock surged in December due to positive data around its Huntington's disease candidate AMT-130, clearing the way for potential accelerated FDA approval without another trial. The company's gene therapy Hemgenix, approved for hemophilia B, and three new clinical programs, including AMT-191, AMT-162, and AMT-260, bolster its pipeline. Cost-cutting measures and strategic financing have extended uniQure's operating runway through 2Q28, with significant analyst support and price targets up to $70 a share.
uniQure N.V.: A Potential Huntington's Play
Positive
Seeking Alpha
1 month ago
uniQure: Gene Therapy Specialist Looks Set For Upside As Huntington's Approval Beckons
uniQure's gene therapy AMT-130 for Huntington's Disease shows promising clinical data, with an 80% reduction in disease progression, positioning it for potential FDA approval. Despite past commercial failures, uniQure's current market cap of ~$715m appears undervalued given AMT-130's estimated peak sales potential of ~$2bn. The company has a solid cash position to fund AMT-130's launch, with $251m in cash and $183m in securities, despite a $100m net loss in the first 9m of 2025.
uniQure: Gene Therapy Specialist Looks Set For Upside As Huntington's Approval Beckons
Positive
Benzinga
2 months ago
uniQure/ CSL Behring's Hemophilia Gene Therapy Shows Sustained Efficacy and Safety At Four Years
CSL Limited CSLLY and uniQure Inc QURE announced the four-year results from the pivotal HOPE-B study confirming the long-term durability and safety of a one-time infusion of Hemgenix (etranacogene dezaparvovec-drlb) for adults hemophilia B patients.
uniQure/ CSL Behring's Hemophilia Gene Therapy Shows Sustained Efficacy and Safety At Four Years
Neutral
PRNewsWire
2 months ago
CSL Behring's Gene Therapy HEMGENIX® (etranacogene dezaparvovec-drlb) Four Years Post-Infusion Data Continue to Show Sustained Efficacy and Safety in Adults with Hemophilia B
94 percent of patients eliminated factor IX prophylaxis and remained free of continuous prophylaxis through four years post-treatment Mean factor IX activity levels were sustained at near normal levels of 37% through four years post-treatment, reinforcing the efficacy of HEMGENIX in the treatment of hemophilia B Phase 3 HOPE-B data showed that a one-time treatment with HEMGENIX provided long-term bleed protection as mean adjusted annualized bleeding rate (ABR) for all bleeds was reduced by approximately 90% from lead-in as compared to year four KING OF PRUSSIA, Pa. , Feb. 7, 2025 /PRNewswire/ -- Global biotechnology leader CSL (ASX:CSL; USOTC:CSLLY) today announced the four-year results from the pivotal HOPE-B study confirming the long-term durability and safety of a one-time infusion of HEMGENIX® (etranacogene dezaparvovec-drlb) for adults living with hemophilia B.
CSL Behring's Gene Therapy HEMGENIX® (etranacogene dezaparvovec-drlb) Four Years Post-Infusion Data Continue to Show Sustained Efficacy and Safety in Adults with Hemophilia B
Neutral
GlobeNewsWire
2 months ago
uniQure Announces Completion of Enrollment in the First Cohort and Favorable Recommendation from the Independent Data Monitoring Committee for its Phase I/IIa Clinical Trial of AMT-191 for the Treatment of Fabry Disease
~ Independent Data Monitoring Committee recommends proceeding with dosing of second cohort after planned safety assessment ~
uniQure Announces Completion of Enrollment in the First Cohort and Favorable Recommendation from the Independent Data Monitoring Committee for its Phase I/IIa Clinical Trial of AMT-191 for the Treatment of Fabry Disease
Neutral
GlobeNewsWire
2 months ago
uniQure Announces Favorable Recommendation from Independent Data Monitoring Committee for its Phase I/II EPISOD1 Clinical Trial of AMT-162 for the Treatment of SOD1-ALS
~ Independent Data Monitoring Committee Recommends Proceeding with Dose Escalation After Planned Safety Assessment of First Dose Cohort ~
uniQure Announces Favorable Recommendation from Independent Data Monitoring Committee for its Phase I/II EPISOD1 Clinical Trial of AMT-162 for the Treatment of SOD1-ALS
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