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uniQure
QURE

Overview Fund Activity

141 hedge funds and large institutions have $728M invested in uniQure in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 43 increasing their positions, 47 reducing their positions, and 29 closing their positions.

Holders
141
Holders Change
+1
Holders Change %
+0.71%
% of All Funds
1.89%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
32
Increased
43
Reduced
47
Closed
29
Calls
$64.5M
Puts
$11.6M
Net Calls
+$52.9M
Net Calls Change
+$35.7M

Top Buyers

1
JFG
1
Jefferies Financial Group
New York
$29.2M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$25.2M
3
ACA
3
Avoro Capital Advisors
New York
$50.5M
4
SI
4
Sofinnova Investments
California
$21.7M
5
RI
5
RTW Investments
New York
$71.9M

Top Sellers

1
VPC
1
Vestal Point Capital
New York
$51.6M
2
NCM
2
Nantahala Capital Management
Connecticut
$28.6M
3
PHS
3
PFM Health Sciences
California
$2.43M
4
CCM
4
Catalio Capital Management
New York
$5.82M
5
Franklin Resources
5
Franklin Resources
California
$22.4M
Name Market Value Shares Shares
Change 		Shares
Change %
RI
1
RTW Investments
New York
$71.9M 5,158,231 +892,803 +21%
EC
2
EcoR1 Capital
California
$55.6M 3,988,971 – –
VPC
3
Vestal Point Capital
New York
$51.6M 3,700,000 -1,092,572 -23%
ACA
4
Avoro Capital Advisors
New York
$50.5M 3,625,000 +1,450,000 +67%
Aberdeen Group
5
Aberdeen Group
United Kingdom
$38.3M 2,750,714 +535,163 +24%
JFG
6
Jefferies Financial Group
New York
$29.2M 2,095,931 +2,095,931 New
NCM
7
Nantahala Capital Management
Connecticut
$28.6M 2,051,852 -704,110 -26%
JPMorgan Chase & Co
8
JPMorgan Chase & Co
New York
$25.2M 1,807,685 +1,491,486 +472%
Franklin Resources
9
Franklin Resources
California
$22.4M 1,605,515 -382,173 -19%
SI
10
Sofinnova Investments
California
$21.7M 1,558,356 +1,012,585 +186%
IHAM
11
Integral Health Asset Management
New York
$18.8M 1,350,000 +100,000 +8%
BlackRock
12
BlackRock
New York
$18.6M 1,333,663 -103,318 -7%
6CM
13
683 Capital Management
New York
$17.9M 1,285,000 -265,000 -17%
Fidelity Investments
14
Fidelity Investments
Massachusetts
$16.5M 1,184,362 -16,582 -1%
State Street
15
State Street
Massachusetts
$15.9M 1,142,810 -86,779 -7%
Vanguard Group
16
Vanguard Group
Pennsylvania
$13.6M 972,691 +27,225 +3%
Two Sigma Investments
17
Two Sigma Investments
New York
$13.1M 940,960 +24,461 +3%
Morgan Stanley
18
Morgan Stanley
New York
$12.7M 908,283 +304,767 +50%
BCM
19
Boxer Capital Management
California
$12.5M 899,500 +149,500 +20%
Ameriprise
20
Ameriprise
Minnesota
$10.6M 761,948 +212,218 +39%
Macquarie Group
21
Macquarie Group
Australia
$9.84M 706,166 – –
Two Sigma Advisers
22
Two Sigma Advisers
New York
$9.2M 659,700 -8,794 -1%
Geode Capital Management
23
Geode Capital Management
Massachusetts
$8.41M 603,210 -7,761 -1%
SC
24
Stempoint Capital
New York
$7.98M 572,615 -158,424 -22%
Citadel Advisors
25
Citadel Advisors
Florida
$7.75M 555,865 -229,455 -29%
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