uniQure
QURE
143 hedge funds and large institutions have $738M invested in uniQure in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 43 increasing their positions, 48 reducing their positions, and 30 closing their positions.
325% more call options, than puts
Call options by funds: $81.3M | Put options by funds: $19.1M
38% more capital invested
Capital invested by funds: $533M → $738M (+$205M)
4.08% more ownership
Funds ownership: 92.61% → 96.69% (+4.1%)
1% more funds holding
Funds holding: 141 → 143 (+2)
7% more first-time investments, than exits
New positions opened: 32 | Existing positions closed: 30
10% less repeat investments, than reductions
Existing positions increased: 43 | Existing positions reduced: 48
33% less funds holding in top 10
Funds holding in top 10: 3 → 2 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
JFG
Jefferies Financial Group
New York
|
+$28.2M |
| 2 |
JP Morgan Chase
New York
|
+$20.1M |
| 3 |
ACA
Avoro Capital Advisors
New York
|
+$19.5M |
| 4 |
SI
Sofinnova Investments
Menlo Park,
California
|
+$13.6M |
| 5 |
RI
RTW Investments
New York
|
+$12M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
VPC
Vestal Point Capital
New York
|
-$14.7M |
| 2 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
-$9.47M |
| 3 |
Schroder Investment Management Group
London,
United Kingdom
|
-$6.68M |
| 4 |
PHS
PFM Health Sciences
San Francisco,
California
|
-$5.73M |
| 5 |
CCM
Catalio Capital Management
New York
|
-$5.55M |
QURE Hedge Fund Activity: Q2 2025 in Review
143 of the 7,613 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q2 2025, worth a combined $738M — up 38% from $533M a quarter earlier.
Buyers outnumbered sellers: 32 funds opened new QURE positions and 30 closed out — a net gain of 2 holders — while 43 added to existing stakes and 48 trimmed.
The largest buyer was Jefferies Financial Group, opening a new position worth an estimated $28.2M. The largest seller was Vestal Point Capital, cutting an estimated $14.7M.
- 143 institutional investors held uniQure (QURE) as of Q2 2025, up from 141 in Q1 2025.
- Funds reported $738M of uniQure stock for Q2 2025, up 38% quarter-over-quarter.
- 32 funds opened new uniQure positions in Q2 2025 and 30 closed out, a net change of +2 holders.
- The largest uniQure buyer in Q2 2025 was Jefferies Financial Group, an estimated $28.2M added.
- The largest uniQure seller in Q2 2025 was Vestal Point Capital, an estimated $14.7M sold.
Based on aggregated 13F filings for Q2 2025.