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uniQure

213 hedge funds and large institutions have $971M invested in uniQure in 2026 Q1 according to their latest regulatory filings, with 47 funds opening new positions, 72 increasing their positions, 61 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

561% more call options, than puts

Call options by funds: $283M | Put options by funds: $42.8M

18% more repeat investments, than reductions

Existing positions increased: 72 | Existing positions reduced: 61

10% less first-time investments, than exits

New positions opened: 47 | Existing positions closed: 52

3.88% less ownership

Funds ownership: 99.32%95.44% (-3.9%)

5% less funds holding

Funds holding: 225213 (-12)

34% less capital invested

Capital invested by funds: $1.48B → $971M (-$510M)

100% less funds holding in top 10

Funds holding in top 10: 30 (-3)

Holders
213
Holders Change
-12
Holders Change %
-5.33%
% of All Funds
2.61%
Holding in Top 10
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-100%
% of All Funds
New
47
Increased
72
Reduced
61
Closed
52
Calls
$283M
Puts
$42.8M
Net Calls
+$240M
Net Calls Change
+$75.3M
Name Holding Trade Value Shares
Change
Change in
Stake
ACA
1
Avoro Capital Advisors
New York
$97.4M -$3.86M -190,405 -3%
Aberdeen Group
2
Aberdeen Group
United Kingdom
$86.8M +$33M +1,627,746 +44%
Two Sigma Investments
3
Two Sigma Investments
New York
$43.8M +$24.8M +1,224,587 +84%
RI
4
RTW Investments
New York
$42.3M -$22.8M -1,125,106 -30%
JP Morgan Chase
5
JP Morgan Chase
New York
$41.8M -$1.97M -97,160 -3%
State Street
6
State Street
Massachusetts
$37M -$19.7M -970,531 -30%
O
7
OrbiMed
New York
$34.9M +$28.3M +1,398,749 +190%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$28.5M -$91.1M -4,497,128 -72%
BlackRock
9
BlackRock
New York
$28.3M -$4.89M -241,530 -12%
MB
10
MPM BioImpact
Massachusetts
$22.4M -$251K -12,397 -0.9%
TSC
11
Two Seas Capital
New York
$21.3M +$26.3M +1,300,000 New
Goldman Sachs
12
Goldman Sachs
New York
$20.7M +$1.94M +95,628 +8%
Jennison Associates
13
Jennison Associates
New York
$20.2M -$2.78M -137,401 -10%
Susquehanna International Group
14
Susquehanna International Group
Pennsylvania
$16.4M -$4.36M -215,550 -18%
SL
15
Siren LLC
Connecticut
$16.4M +$20.2M +1,000,000 New
Balyasny Asset Management
16
Balyasny Asset Management
Illinois
$15.8M +$16.8M +828,646 +611%
IHAM
17
Integral Health Asset Management
New York
$14.7M
Fiera Capital (Canada)
18
Fiera Capital (Canada)
Quebec, Canada
$13.4M +$980K +48,383 +6%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$13.2M +$578K +28,539 +4%
Millennium Management
20
Millennium Management
New York
$13M -$220K -10,849 -1%
SG Americas Securities
21
SG Americas Securities
New York
$12.7M +$14.4M +712,278 +1,107%
MC
22
Maverick Capital
Texas
$11.4M +$725K +35,820 +5%
Vanguard Capital Management
23
Vanguard Capital Management
Pennsylvania
$11.4M +$14.1M +694,721 New
BCM
24
Boxer Capital Management
California
$10.8M +$7.53M +372,000 +128%
WCM
25
Whitefort Capital Management
New York
$10.8M +$4.02M +198,611 +43%

QURE Hedge Fund Activity: Q1 2026 in Review

213 of the 8,172 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q1 2026, worth a combined $971M — down 34% from $1.48B a quarter earlier.

Sellers outnumbered buyers: 52 funds closed out of QURE and 47 opened new positions — a net loss of 5 holders — while 61 trimmed existing stakes and 72 added.

The largest buyer was Aberdeen Group, adding an estimated $33M. The largest seller was Fidelity Investments, cutting an estimated $91.1M.

  • 213 institutional investors held uniQure (QURE) as of Q1 2026, down from 225 in Q4 2025.
  • Funds reported $971M of uniQure stock for Q1 2026, down 34% quarter-over-quarter.
  • 47 funds opened new uniQure positions in Q1 2026 and 52 closed out, a net change of -5 holders.
  • The largest uniQure buyer in Q1 2026 was Aberdeen Group, an estimated $33M added.
  • The largest uniQure seller in Q1 2026 was Fidelity Investments, an estimated $91.1M sold.

Based on aggregated 13F filings for Q1 2026.