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uniQure

224 hedge funds and large institutions have $1.48B invested in uniQure in 2025 Q4 according to their latest regulatory filings, with 72 funds opening new positions, 72 increasing their positions, 61 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

260% more call options, than puts

Call options by funds: $228M | Put options by funds: $63.5M

18% more repeat investments, than reductions

Existing positions increased: 72 | Existing positions reduced: 61

14% more first-time investments, than exits

New positions opened: 72 | Existing positions closed: 63

3% more funds holding

Funds holding: 218224 (+6)

1.58% less ownership

Funds ownership: 100.88%99.3% (-1.6%)

54% less capital invested

Capital invested by funds: $3.23B → $1.48B (-$1.75B)

80% less funds holding in top 10

Funds holding in top 10: 153 (-12)

Holders
224
Holders Change
+6
Holders Change %
+2.75%
% of All Funds
2.72%
Holding in Top 10
3
Holding in Top 10 Change
-12
Holding in Top 10 Change %
-80%
% of All Funds
0.04%
New
72
Increased
72
Reduced
61
Closed
63
Calls
$228M
Puts
$63.5M
Net Calls
+$165M
Net Calls Change
+$155M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$149M +$7M +181,362 +3%
ACA
2
Avoro Capital Advisors
New York
$147M +$65.8M +1,705,556 +38%
RI
3
RTW Investments
New York
$88.8M -$27.5M -713,506 -16%
Aberdeen Group
4
Aberdeen Group
United Kingdom
$88M +$28.5M +738,897 +25%
State Street
5
State Street
Massachusetts
$77.3M +$69M +1,787,033 +124%
JP Morgan Chase
6
JP Morgan Chase
New York
$70.2M +$68.9M +1,785,275 +155%
BlackRock
7
BlackRock
New York
$47.3M +$20.4M +528,889 +37%
Two Sigma Investments
8
Two Sigma Investments
New York
$34.7M +$21.4M +553,746 +62%
MB
9
MPM BioImpact
Massachusetts
$33.1M +$53.3M +1,381,628 New
Jennison Associates
10
Jennison Associates
New York
$32.8M +$14.3M +371,706 +37%
Susquehanna International Group
11
Susquehanna International Group
Pennsylvania
$29.2M +$38.3M +992,810 +440%
SCM
12
Suvretta Capital Management
New York
$29.1M +$47M +1,216,734 New
Goldman Sachs
13
Goldman Sachs
New York
$27.9M +$19.5M +505,400 +76%
Two Sigma Advisers
14
Two Sigma Advisers
New York
$26.6M +$27M +700,900 +171%
Vanguard Group
15
Vanguard Group
Pennsylvania
$25.2M -$2.85M -73,729 -7%
AGP
16
Artia Global Partners
Florida
$24.5M +$14.1M +364,700 +55%
IHAM
17
Integral Health Asset Management
New York
$21.5M +$11.6M +300,000 +50%
Millennium Management
18
Millennium Management
New York
$19.2M +$23.6M +612,005 +319%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$18.6M +$2.1M +54,419 +8%
Fiera Capital (Canada)
20
Fiera Capital (Canada)
Quebec, Canada
$18.4M +$29.7M +768,510 New
Franklin Resources
21
Franklin Resources
California
$17.9M -$47.9M -1,241,979 -62%
O
22
OrbiMed
New York
$17.6M +$10.8M +278,900 +61%
Morgan Stanley
23
Morgan Stanley
New York
$17.2M +$15.3M +395,426 +123%
NCM
24
Nantahala Capital Management
Connecticut
$16.7M -$11.9M -308,194 -31%
LGM
25
Logos Global Management
California
$16.2M +$14.5M +375,000 +125%