EcoR1 Capital’s uniQure QURE Stock Holding History

EcoR1 Capital’s Portfolio QURE Stock Details QURE Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-3,988,971	Closed	-$233M	–	38
2025 Q3	$233M	Hold	3,988,971	–	–	11.17%	3
2025 Q2	$55.6M	Hold	3,988,971	–	–	3.29%	8
2025 Q1	$42.3M	Buy	3,988,971 +588,971	+17%	+$8.26M	2.51%	10
2024 Q4	$60M	Buy	+3,400,000	New	+$29.4M	2.27%	12

Other funds holding QURE

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return

Aberdeen Group Edinburgh, United Kingdom $71.2B AUM 41.74% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return

MPM BioImpact Boston, Massachusetts $1.64B AUM 245.64% 1-Year Est. Return

Jennison Associates New York $167B AUM 44.17% 1-Year Est. Return

EcoR1 Capital's QURE Position: Q4 2025 in Review

EcoR1 Capital sold out of uniQure (QURE) in Q4 2025, closing a stake of 3,988,971 shares — an estimated $233M sold.

EcoR1 Capital first reported a position in QURE in Q4 2024 and held it in 4 quarters. The position peaked at $233M in Q3 2025. 226 funds tracked by Wall St. Rank hold QURE as of Q4 2025.

EcoR1 Capital reported no remaining uniQure position as of Q4 2025 after selling out during the quarter.
EcoR1 Capital sold 3,988,971 uniQure shares in Q4 2025, an estimated $233M.
EcoR1 Capital first reported a position in uniQure in Q4 2024 and held it in 4 quarters.
EcoR1 Capital's uniQure position peaked at $233M in Q3 2025.
226 funds tracked by Wall St. Rank held uniQure as of Q4 2025.

Based on EcoR1 Capital's 13F filing for Q4 2025, filed 17 Feb 2026.