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Mid Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
ZBIO
76
Zenas BioPharma
ZBIO
$2.2B
$2.2B $33.77 6.7%
XNCR icon
77
Xencor
XNCR
$2.18B
$2.18B $29.30 1.03%
ADMA icon
78
ADMA Biologics
ADMA
$2.18B
$2.18B $9.72 1.78%
BHVN icon
79
Biohaven
BHVN
$2.17B
$2.17B $14.38 5.12%
STOK icon
80
Stoke Therapeutics
STOK
$2.16B
$2.16B $33.46 3.53%
PVLA
81
Palvella Therapeutics
PVLA
$2.14B
$2.14B $148.24 1.71%
NBTX
82
Nanobiotix
NBTX
$2.11B
$2.11B $41.51 4.66%
AGIO icon
83
Agios Pharmaceuticals
AGIO
$2.02B
$2.02B $33.90 3.86%
TSHA icon
84
Taysha Gene Therapies
TSHA
$2.02B
$2.02B $6.20 3.85%

Mid Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 84 mid cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $2B and $10B — worth a combined $356B.

The largest by market cap are Protagonist Therapeutics (PTGX) at $9.74B, Spyre Therapeutics (SYRE) at $9.47B and Vaxcyte (PCVX) at $9.09B.

Among institutional investors, Definium Therapeutics (DFTX) drew the most net new fund positions in Q2 2026: 148 funds opened new positions, taking total fund holders up 114 (46%) quarter-over-quarter.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.