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Small Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
RZLT icon
151
Rezolute
RZLT
$370M
$370M $3.84 2.78%
DMAC icon
152
DiaMedica Therapeutics
DMAC
$369M
$369M $6.85 0%
OBIO icon
153
Orchestra BioMed
OBIO
$365M
$365M $6.08 5.19%
OCGN icon
154
Ocugen
OCGN
$359M
$359M $1.06 2.91%
ENTA icon
155
Enanta Pharmaceuticals
ENTA
$355M
$355M $12.20 2.56%
XFOR icon
156
X4 Pharmaceuticals
XFOR
$355M
$355M $3.58 2.29%
AGEN
157
Agenus
AGEN
$355M
$355M $7.85 8.73%
EVMN
158
Evommune Inc
EVMN
$350M
$350M $9.65 2.99%
LXEO icon
159
Lexeo Therapeutics
LXEO
$345M
$345M $4.20 0.48%
CMPX icon
160
Compass Therapeutics
CMPX
$342M
$342M $1.90 2.7%
IPSC icon
161
Century Therapeutics
IPSC
$337M
$337M $1.86 1.06%
EYPT icon
162
EyePoint Inc
EYPT
$332M
$332M $3.85 3.51%
IKT icon
163
Inhibikase Therapeutics
IKT
$321M
$321M $2.30 0%
SABS icon
164
SAB Biotherapeutics
SABS
$319M
$319M $3.51 0.29%
ABEO icon
165
Abeona Therapeutics
ABEO
$319M
$319M $5.57 0.36%
QTTB icon
166
Q32 Bio
QTTB
$314M
$314M $10.54 2.95%
VNDA icon
167
Vanda Pharmaceuticals
VNDA
$310M
$310M $5.13 0.39%
IFRX icon
168
InflaRx
IFRX
$308M
$308M $2.09 1.46%
FATE icon
169
Fate Therapeutics
FATE
$303M
$303M $2.53 0.4%
CUVL
170
Clinuvel Pharmaceuticals
CUVL
$298M
$298M $5.90 0.68%
ZNTL icon
171
Zentalis Pharmaceuticals
ZNTL
$294M
$294M $3.11 0.97%
UPB
172
Upstream Bio Inc
UPB
$292M
$292M $5.34 0.56%
VCRE
173
Vicore Pharma Holding AB ADS
VCRE
$291M
$291M $10.35 0.48%
IMRX icon
174
Immuneering
IMRX
$290M
$290M $4.48 0.45%
FULC icon
175
Fulcrum Therapeutics
FULC
$287M
$287M $3.76 0.27%
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Small Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 188 small cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $250M and $2B — worth a combined $157B.

The largest by market cap are Agios Pharmaceuticals (AGIO) at $1.97B, Mesoblast (MESO) at $1.96B and Rapport Therapeutics (RAPP) at $1.94B.

Among institutional investors, First Tracks Biotherapeutics (TRAX) drew the most net new fund positions in Q2 2026: 149 funds opened new positions.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.