|
1
|
EcoR1 Capital
San Francisco,
California
|
$288M
|
+$68M
|
+5,710,840
|
+33%
|
|
|
2
|
Rubric Capital Management (New York)
New York
|
$59.1M
|
+$4.43M
|
+372,107
|
+9%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$54.1M
|
–
|
–
|
–
|
|
|
4
|
|
$52.4M
|
+$1.24M
|
+104,151
|
+3%
|
|
|
5
|
Redmile Group
San Francisco,
California
|
$52.1M
|
-$7.6M
|
-638,318
|
-13%
|
|
|
6
|
|
$47.6M
|
-$3.52M
|
-295,149
|
-7%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$30.9M
|
+$8.31M
|
+697,652
|
+39%
|
|
|
8
|
|
$30.9M
|
-$16.9M
|
-1,420,432
|
-37%
|
|
|
9
|
BNP Paribas Asset Management
Paris,
France
|
$25.6M
|
-$1.88M
|
-158,223
|
-7%
|
|
|
10
|
|
$20.8M
|
+$3.27M
|
+274,203
|
+20%
|
|
|
11
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$19.4M
|
-$93.5K
|
-7,849
|
-0.5%
|
|
|
12
|
Prosight Management
Dallas,
Texas
|
$16.4M
|
+$4.2M
|
+352,675
|
+37%
|
|
|
13
|
Perceptive Advisors
New York
|
$16M
|
-$7.02M
|
-589,398
|
-32%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$15M
|
+$1.35M
|
+112,974
|
+10%
|
|
|
15
|
Vestal Point Capital
New York
|
$14.4M
|
+$7.74M
|
+650,000
|
+130%
|
|
|
16
|
Nextech Invest
Zurich,
Switzerland
|
$14M
|
–
|
–
|
–
|
|
|
17
|
Tang Capital Management
San Diego,
California
|
$13.8M
|
–
|
–
|
–
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$13.7M
|
+$39.6K
|
+3,326
|
+0.3%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$8.85M
|
+$3.92K
|
+329
|
+0%
|
|
|
20
|
Nuveen
Charlotte,
North Carolina
|
$8.22M
|
+$5.43M
|
+456,104
|
+229%
|
|
|
21
|
Renaissance Technologies
New York
|
$6.69M
|
+$985K
|
+82,700
|
+18%
|
|
|
22
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$6.18M
|
-$27.2K
|
-2,287
|
-0.5%
|
|
|
23
|
Adage Capital Partners
Boston,
Massachusetts
|
$5.97M
|
+$5.67M
|
+476,000
|
New
|
|
|
24
|
|
$5.54M
|
+$4.8M
|
+403,281
|
+1,050%
|
|
|
25
|
|
$5.38M
|
+$2.73M
|
+228,810
|
+114%
|
|
