|
1
|
EcoR1 Capital
San Francisco,
California
|
$605M
|
–
|
–
|
–
|
|
|
2
|
Rubric Capital Management (New York)
New York
|
$151M
|
+$22.7M
|
+1,039,449
|
+22%
|
|
|
3
|
|
$121M
|
+$13.2M
|
+606,015
|
+15%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$104M
|
–
|
–
|
–
|
|
|
5
|
Perceptive Advisors
New York
|
$85.9M
|
+$25.5M
|
+1,171,187
|
+56%
|
|
|
6
|
|
$68.3M
|
-$30.4M
|
-1,391,505
|
-35%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$61.3M
|
+$3.8M
|
+174,293
|
+8%
|
|
|
8
|
BNP Paribas Asset Management
Paris,
France
|
$48M
|
+$39.7M
|
+1,822,048
|
New
|
|
|
9
|
Siren LLC
Greenwich,
Connecticut
|
$44.2M
|
+$36.6M
|
+1,680,121
|
New
|
|
|
10
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$42M
|
+$1.11M
|
+50,935
|
+3%
|
|
|
11
|
Dimensional Fund Advisors
Austin,
Texas
|
$30.5M
|
-$690K
|
-31,623
|
-3%
|
|
|
12
|
Nextech Invest
Zurich,
Switzerland
|
$29.3M
|
–
|
–
|
–
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$27.3M
|
-$950K
|
-43,547
|
-4%
|
|
|
14
|
Capricorn Fund Managers
London,
United Kingdom
|
$26.9M
|
+$22.3M
|
+1,022,840
|
New
|
|
|
15
|
Vestal Point Capital
New York
|
$22.8M
|
-$19.6M
|
-900,000
|
-51%
|
|
|
16
|
Arrowstreet Capital
Boston,
Massachusetts
|
$18.4M
|
+$8.42M
|
+386,249
|
+123%
|
|
|
17
|
Adage Capital Partners
Boston,
Massachusetts
|
$17.5M
|
+$2.17M
|
+99,546
|
+18%
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$17.1M
|
+$1.81M
|
+82,941
|
+15%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$17.1M
|
-$669K
|
-30,666
|
-5%
|
|
|
20
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$17M
|
-$14.8M
|
-679,400
|
-51%
|
|
|
21
|
Fidelity Investments
Boston,
Massachusetts
|
$14.7M
|
+$12.1M
|
+556,572
|
+15,839%
|
|
|
22
|
Prosight Management
Dallas,
Texas
|
$14M
|
-$4.78M
|
-219,218
|
-29%
|
|
|
23
|
Redmile Group
San Francisco,
California
|
$12.9M
|
-$70.1M
|
-3,214,096
|
-87%
|
|
|
24
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
$12.5M
|
+$4.78M
|
+219,288
|
+86%
|
|
|
25
|
Algert Global
San Francisco,
California
|
$11.2M
|
+$4.71M
|
+215,720
|
+104%
|
|
