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Zymeworks
ZYME

Overview Fund Activity

178 hedge funds and large institutions have $942M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 53 reducing their positions, and 30 closing their positions.

Holders
178
Holders Change
-5
Holders Change %
-2.73%
% of All Funds
2.39%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
53
Closed
30
Calls
$3.35M
Puts
$208K
Net Calls
+$3.14M
Net Calls Change
-$26K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
EC
1
EcoR1 Capital
California
$288M 22,970,388 +5,710,840 +33%
RCMNY
2
Rubric Capital Management (New York)
New York
$59.1M 4,710,551 +372,107 +9%
BI
3
BVF Inc
California
$54.1M 4,308,935 – –
Morgan Stanley
4
Morgan Stanley
New York
$52.4M 4,177,614 +104,151 +3%
RG
5
Redmile Group
California
$52.1M 4,150,627 -638,318 -13%
BlackRock
6
BlackRock
New York
$47.6M 3,794,272 -295,149 -7%
Vanguard Group
7
Vanguard Group
Pennsylvania
$30.9M 2,464,693 +697,652 +39%
UBS AM
8
UBS AM
Illinois
$30.9M 2,459,513 -1,420,432 -37%
BNP Paribas Asset Management
9
BNP Paribas Asset Management
France
$25.6M 2,039,656 -158,223 -7%
Blackstone Inc
10
Blackstone Inc
New York
$20.8M 1,656,790 +274,203 +20%
Deutsche Bank
11
Deutsche Bank
Germany
$19.4M 1,544,763 -7,849 -0.5%
PM
12
Prosight Management
Texas
$16.4M 1,309,904 +352,675 +37%
PA
13
Perceptive Advisors
New York
$16M 1,275,274 -589,398 -32%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$15M 1,192,432 +112,974 +10%
VPC
15
Vestal Point Capital
New York
$14.4M 1,150,000 +650,000 +130%
NI
16
Nextech Invest
Switzerland
$14M 1,113,946 – –
TCM
17
Tang Capital Management
California
$13.8M 1,100,000 – –
State Street
18
State Street
Massachusetts
$13.7M 1,088,459 +3,326 +0.3%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$8.85M 705,364 +329 +0%
NL
20
Nuveen LLC
North Carolina
$8.22M 654,916 +456,104 +229%
Renaissance Technologies
21
Renaissance Technologies
New York
$6.69M 533,300 +82,700 +18%
Assenagon Asset Management
22
Assenagon Asset Management
Luxembourg
$6.18M 492,780 -2,287 -0.5%
Adage Capital Partners
23
Adage Capital Partners
Massachusetts
$5.97M 476,000 +476,000 New
JPMorgan Chase & Co
24
JPMorgan Chase & Co
New York
$5.54M 441,690 +403,281 +1,050%
Goldman Sachs
25
Goldman Sachs
New York
$5.38M 428,857 +228,810 +114%
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