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Zymeworks

172 hedge funds and large institutions have $973M invested in Zymeworks in 2024 Q4 according to their latest regulatory filings, with 31 funds opening new positions, 47 increasing their positions, 61 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

150% more funds holding in top 10

Funds holding in top 10: 25 (+3)

106% more call options, than puts

Call options by funds: $547K | Put options by funds: $266K

55% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 20

17% more capital invested

Capital invested by funds: $835M → $973M (+$139M)

6% more funds holding

Funds holding: 163172 (+9)

2.81% more ownership

Funds ownership: 93.7%96.52% (+2.8%)

23% less repeat investments, than reductions

Existing positions increased: 47 | Existing positions reduced: 61

Holders
172
Holders Change
+9
Holders Change %
+5.52%
% of All Funds
2.27%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.07%
New
31
Increased
47
Reduced
61
Closed
20
Calls
$547K
Puts
$266K
Net Calls
+$281K
Net Calls Change
+$7.41M
Name Holding Trade Value Shares
Change
Change in
Stake
EC
1
EcoR1 Capital
California
$220M +$22.2M +1,590,606 +12%
RG
2
Redmile Group
California
$70.9M -$3.66M -261,448 -5%
BI
3
BVF Inc
California
$63.1M -$4.18M -299,000 -6%
Morgan Stanley
4
Morgan Stanley
New York
$61.5M -$12.7M -905,432 -18%
BlackRock
5
BlackRock
New York
$61.3M -$1.1M -78,639 -2%
RCMNY
6
Rubric Capital Management (New York)
New York
$57.3M
Vanguard Group
7
Vanguard Group
Pennsylvania
$36.5M -$5.11M -365,226 -13%
BNP Paribas Asset Management
8
BNP Paribas Asset Management
France
$31.3M +$2.69M +192,162 +10%
PA
9
Perceptive Advisors
New York
$31.2M -$699K -50,000 -2%
Deutsche Bank
10
Deutsche Bank
Germany
$22.6M +$250K +17,849 +1%
UBS AM
11
UBS AM
Illinois
$20M -$2.22M -158,973 -10%
FCM
12
Farallon Capital Management
California
$19.5M -$434K -31,026 -2%
NI
13
Nextech Invest
Switzerland
$16.3M
TCM
14
Tang Capital Management
California
$16.1M
State Street
15
State Street
Massachusetts
$15.9M -$1.21M -86,816 -7%
SB
16
Samsara BioCapital
California
$14.6M
Dimensional Fund Advisors
17
Dimensional Fund Advisors
Texas
$14.2M +$1.72M +123,240 +15%
PM
18
Prosight Management
Texas
$12M -$1.36M -97,599 -11%
BCM
19
Bridgeway Capital Management
Texas
$11.1M +$239K +17,092 +2%
Geode Capital Management
20
Geode Capital Management
Massachusetts
$10.1M -$336K -24,031 -3%
Assenagon Asset Management
21
Assenagon Asset Management
Luxembourg
$9.4M +$4.35M +311,107 +94%
Blackstone Inc
22
Blackstone Inc
New York
$8.34M +$7.62M +544,633 +2,171%
Walleye Capital
23
Walleye Capital
New York
$6.63M +$6.33M +452,804 New
GIM
24
Granahan Investment Management
Massachusetts
$6.02M -$2.83M -202,383 -33%
Northern Trust
25
Northern Trust
Illinois
$5.78M +$334K +23,903 +6%

ZYME Hedge Fund Activity: Q4 2024 in Review

172 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Zymeworks (ZYME) for Q4 2024, worth a combined $973M — up 17% from $835M a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new ZYME positions and 20 closed out — a net gain of 11 holders — while 47 added to existing stakes and 61 trimmed.

The largest buyer was EcoR1 Capital, adding an estimated $22.2M. The largest seller was Morgan Stanley, cutting an estimated $12.7M.

  • 172 institutional investors held Zymeworks (ZYME) as of Q4 2024, up from 163 in Q3 2024.
  • Funds reported $973M of Zymeworks stock for Q4 2024, up 17% quarter-over-quarter.
  • 31 funds opened new Zymeworks positions in Q4 2024 and 20 closed out, a net change of +11 holders.
  • The largest Zymeworks buyer in Q4 2024 was EcoR1 Capital, an estimated $22.2M added.
  • The largest Zymeworks seller in Q4 2024 was Morgan Stanley, an estimated $12.7M sold.

Based on aggregated 13F filings for Q4 2024.