|
1
|
EcoR1 Capital
San Francisco,
California
|
$600M
|
–
|
–
|
–
|
|
|
2
|
Rubric Capital Management (New York)
New York
|
$183M
|
–
|
–
|
–
|
|
|
3
|
|
$111M
|
-$7.7M
|
-302,858
|
-7%
|
|
|
4
|
Perceptive Advisors
New York
|
$109M
|
+$17.1M
|
+672,875
|
+19%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$95.4M
|
-$2.16M
|
-85,000
|
-2%
|
|
|
6
|
|
$58.3M
|
-$6.33M
|
-249,308
|
-10%
|
|
|
7
|
BNP Paribas Asset Management
Paris,
France
|
$46.6M
|
-$3.22M
|
-126,923
|
-7%
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$40.8M
|
-$3.72M
|
-146,582
|
-9%
|
|
|
9
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$32.7M
|
+$13.3M
|
+524,041
|
+72%
|
|
|
10
|
Nextech Invest
Zurich,
Switzerland
|
$29.1M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$28.4M
|
+$1.94M
|
+76,439
|
+8%
|
|
|
12
|
Dimensional Fund Advisors
Austin,
Texas
|
$26M
|
-$3.66M
|
-144,180
|
-13%
|
|
|
13
|
Citadel Advisors
Miami,
Florida
|
$23.9M
|
-$5.99M
|
-235,882
|
-21%
|
|
|
14
|
Nomura Asset Management International
Philadelphia,
Pennsylvania
|
$23.3M
|
+$22.6M
|
+889,802
|
New
|
|
|
15
|
Fidelity Investments
Boston,
Massachusetts
|
$18.4M
|
+$900K
|
+35,415
|
+5%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$18.1M
|
+$825K
|
+32,470
|
+5%
|
|
|
17
|
Prosight Management
Dallas,
Texas
|
$17.6M
|
+$3.44M
|
+135,385
|
+25%
|
|
|
18
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
$15.5M
|
+$2.07M
|
+81,653
|
+16%
|
|
|
19
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$13.3M
|
+$258K
|
+10,157
|
+2%
|
|
|
20
|
Redmile Group
San Francisco,
California
|
$12.9M
|
–
|
–
|
–
|
|
|
21
|
Capricorn Fund Managers
London,
United Kingdom
|
$12.7M
|
-$13.2M
|
-520,681
|
-52%
|
|
|
22
|
|
$12.3M
|
-$3.27M
|
-128,664
|
-21%
|
|
|
23
|
Arrowstreet Capital
Boston,
Massachusetts
|
$10.9M
|
-$8.27M
|
-325,401
|
-44%
|
|
|
24
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$10.4M
|
-$13.3M
|
-524,060
|
-57%
|
|
|
25
|
Hillsdale Investment Management
Toronto,
Ontario, Canada
|
$10M
|
+$948K
|
+37,300
|
+11%
|
|
