|
1
|
EcoR1 Capital
San Francisco,
California
|
$575M
|
–
|
–
|
–
|
|
|
2
|
Rubric Capital Management (New York)
New York
|
$175M
|
+$29.6M
|
+1,250,000
|
+22%
|
|
|
3
|
|
$114M
|
-$986K
|
-41,660
|
-0.9%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$93.5M
|
-$4.84M
|
-204,499
|
-5%
|
|
|
5
|
Perceptive Advisors
New York
|
$87.9M
|
+$5.87M
|
+248,228
|
+8%
|
|
|
6
|
|
$62.1M
|
-$2.66M
|
-112,512
|
-4%
|
|
|
7
|
BNP Paribas Asset Management
Paris,
France
|
$47.8M
|
+$2.03M
|
+85,991
|
+5%
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$42.7M
|
+$40.4M
|
+1,705,580
|
New
|
|
|
9
|
Citadel Advisors
Miami,
Florida
|
$28.8M
|
+$21.2M
|
+894,667
|
+350%
|
|
|
10
|
Dimensional Fund Advisors
Austin,
Texas
|
$28.5M
|
-$475K
|
-20,080
|
-2%
|
|
|
11
|
Nextech Invest
Zurich,
Switzerland
|
$27.9M
|
–
|
–
|
–
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$25.3M
|
-$612K
|
-25,865
|
-2%
|
|
|
13
|
Capricorn Fund Managers
London,
United Kingdom
|
$25.2M
|
-$370K
|
-15,630
|
-2%
|
|
|
14
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$23.1M
|
-$16M
|
-674,583
|
-42%
|
|
|
15
|
Arrowstreet Capital
Boston,
Massachusetts
|
$18.6M
|
+$1.04M
|
+43,896
|
+6%
|
|
|
16
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$18.2M
|
+$1.91M
|
+80,612
|
+12%
|
|
|
17
|
Fidelity Investments
Boston,
Massachusetts
|
$16.7M
|
+$2.53M
|
+107,067
|
+19%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$16.5M
|
+$283K
|
+11,970
|
+2%
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$16.3M
|
+$78.9K
|
+3,336
|
+0.5%
|
|
|
20
|
|
$15M
|
+$4.24M
|
+179,279
|
+43%
|
|
|
21
|
MPM BioImpact
Boston,
Massachusetts
|
$14.2M
|
+$13.4M
|
+565,249
|
New
|
|
|
22
|
Prosight Management
Dallas,
Texas
|
$13.5M
|
+$205K
|
+8,656
|
+2%
|
|
|
23
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
$12.8M
|
+$891K
|
+37,647
|
+8%
|
|
|
24
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$12.5M
|
+$11.8M
|
+499,875
|
New
|
|
|
25
|
Redmile Group
San Francisco,
California
|
$12.3M
|
–
|
–
|
–
|
|
