State Street
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State Street’s Zymeworks ZYME Stock Holding History

State Street’s Portfolio ZYME Stock Details ZYME Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$25.3M Sell
1,011,777
-25,865
-2% -$612K ﹤0.01% 2117
2025
Q4 		$27.3M Sell
1,037,642
-43,547
-4% -$950K ﹤0.01% 2085
2025
Q3 		$18.5M Sell
1,081,189
-7,270
-0.7% -$104K ﹤0.01% 2297
2025
Q2 		$13.7M Buy
1,088,459
+3,326
+0.3% +$39.6K ﹤0.01% 2401
2025
Q1 		$12.9M Buy
1,085,133
+172
+0% +$2.35K ﹤0.01% 2367
2024
Q4 		$15.9M Sell
1,084,961
-86,816
-7% -$1.21M ﹤0.01% 2346
2024
Q3 		$14.7M Buy
1,171,777
+67,401
+6% +$734K ﹤0.01% 2380
2024
Q2 		$9.4M Buy
1,104,376
+55,644
+5% +$495K ﹤0.01% 2594
2024
Q1 		$11M Buy
1,048,732
+40,920
+4% +$454K ﹤0.01% 2525
2023
Q4 		$10.5M Buy
1,007,812
+70,710
+8% +$564K ﹤0.01% 2565
2023
Q3 		$5.94M Buy
937,102
+30,777
+3% +$227K ﹤0.01% 2843
2023
Q2 		$7.83M Buy
906,325
+753,308
+492% +$6.74M ﹤0.01% 2774
2023
Q1 		$1.38M Buy
153,017
+51,032
+50% +$445K ﹤0.01% 3441
2022
Q4 		$802K Buy
101,985
+2,622
+3% +$18.4K ﹤0.01% 3616
2022
Q3 		$611K Buy
99,363
+47,785
+93% +$288K ﹤0.01% 3702
2022
Q2 		$273K Sell
51,578
-85,693
-62% -$518K ﹤0.01% 4077
2022
Q1 		$899K Buy
137,271
+12,061
+10% +$107K ﹤0.01% 3846
2021
Q4 		$2.05M Buy
125,210
+7,356
+6% +$153K ﹤0.01% 3633
2021
Q3 		$3.42M Buy
117,854
+8,252
+8% +$274K ﹤0.01% 3426
2021
Q2 		$3.8M Buy
109,602
+511
+0.5% +$16.2K ﹤0.01% 3365
2021
Q1 		$3.44M Buy
109,091
+1,528
+1% +$62.1K ﹤0.01% 3205
2020
Q4 		$5.08M Sell
107,563
-681
-0.6% -$31.6K ﹤0.01% 2951
2020
Q3 		$5.04M Buy
108,244
+26,276
+32% +$902K ﹤0.01% 2778
2020
Q2 		$2.96M Buy
81,968
+70,180
+595% +$2.58M ﹤0.01% 3019
2020
Q1 		$418K Sell
11,788
-428
-4% -$17.5K ﹤0.01% 3482
2019
Q4 		$555K Sell
12,216
-184
-1% -$6.69K ﹤0.01% 3508
2019
Q3 		$308K Buy
+12,400
New +$311K ﹤0.01% 3562

Other funds holding ZYME

EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
BNP Paribas Asset Management
BNP Paribas Asset Management Paris, France $86.1B AUM 29.11% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return

State Street's ZYME Position: Q1 2026 in Review

State Street reduced its Zymeworks (ZYME) stake by 2.5% in Q1 2026, selling an estimated $612K and leaving 1,011,777 shares worth $25.3M. The position accounts for ﹤0.01% of the portfolio, ranked #2117.

State Street first reported a position in ZYME in Q3 2019 and has held it in 27 quarters since. The position peaked at $27.3M in Q4 2025. 211 funds tracked by Wall St. Rank hold ZYME as of Q1 2026.

  • State Street held 1,011,777 shares of Zymeworks worth $25.3M as of Q1 2026.
  • State Street sold 25,865 Zymeworks shares in Q1 2026, an estimated $612K.
  • Zymeworks made up ﹤0.01% of State Street's portfolio in Q1 2026, its #2117 holding.
  • State Street first reported a position in Zymeworks in Q3 2019 and has held it in 27 quarters since.
  • State Street's Zymeworks position peaked at $27.3M in Q4 2025.
  • 211 funds tracked by Wall St. Rank held Zymeworks as of Q1 2026.

Based on State Street's 13F filing for Q1 2026, filed 15 May 2026.