Zymeworks
ZYME
203 hedge funds and large institutions have $1.79B invested in Zymeworks in 2026 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 61 increasing their positions, 73 reducing their positions, and 29 closing their positions.
38% more call options, than puts
Call options by funds: $4.79M | Put options by funds: $3.48M
1% more capital invested
Capital invested by funds: $1.76B → $1.79B (+$25.7M)
1.7% less ownership
Funds ownership: 95.31% → 93.62% (-1.7%)
4% less funds holding
Funds holding: 212 → 203 (-9)
14% less first-time investments, than exits
New positions opened: 25 | Existing positions closed: 29
16% less repeat investments, than reductions
Existing positions increased: 61 | Existing positions reduced: 73
40% less funds holding in top 10
Funds holding in top 10: 5 → 3 (-2)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
NAMI
Nomura Asset Management International
Philadelphia,
Pennsylvania
|
+$22.6M |
| 2 |
PA
Perceptive Advisors
New York
|
+$17.1M |
| 3 |
Assenagon Asset Management
Senningerberg,
Luxembourg
|
+$13.3M |
| 4 |
First Trust Advisors
Wheaton,
Illinois
|
+$8.65M |
| 5 |
Pictet Asset Management
Carouge,
Switzerland
|
+$7.6M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
MB
MPM BioImpact
Boston,
Massachusetts
|
-$14.2M |
| 2 |
Nuveen
Charlotte,
North Carolina
|
-$13.5M |
| 3 |
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
-$13.3M |
| 4 |
CFM
Capricorn Fund Managers
London,
United Kingdom
|
-$13.2M |
| 5 |
Arrowstreet Capital
Boston,
Massachusetts
|
-$8.27M |
ZYME Hedge Fund Activity: Q2 2026 in Review
203 of the 8,299 institutional investors tracked by Wall St. Rank reported a position in Zymeworks (ZYME) for Q2 2026, worth a combined $1.79B — up 1.5% from $1.76B a quarter earlier.
Sellers outnumbered buyers: 29 funds closed out of ZYME and 25 opened new positions — a net loss of 4 holders — while 73 trimmed existing stakes and 61 added.
The largest buyer was Nomura Asset Management International, opening a new position worth an estimated $22.6M. The largest seller was MPM BioImpact, exiting entirely with an estimated $14.2M sold.
- 203 institutional investors held Zymeworks (ZYME) as of Q2 2026, down from 212 in Q1 2026.
- Funds reported $1.79B of Zymeworks stock for Q2 2026, up 1.5% quarter-over-quarter.
- 25 funds opened new Zymeworks positions in Q2 2026 and 29 closed out, a net change of -4 holders.
- The largest Zymeworks buyer in Q2 2026 was Nomura Asset Management International, an estimated $22.6M added.
- The largest Zymeworks seller in Q2 2026 was MPM BioImpact, an estimated $14.2M sold.
Based on aggregated 13F filings for Q2 2026.