Renaissance Technologies
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Renaissance Technologies’s Zymeworks ZYME Stock Holding History

Renaissance Technologies’s Portfolio ZYME Stock Details ZYME Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-220,877
Closed -$5.82M – 3757
2025
Q4 		$5.82M Sell
220,877
-210,823
-49% -$4.6M 0.01% 1209
2025
Q3 		$7.37M Sell
431,700
-101,600
-19% -$1.45M 0.01% 1254
2025
Q2 		$6.69M Buy
533,300
+82,700
+18% +$985K 0.01% 1324
2025
Q1 		$5.37M Buy
450,600
+164,900
+58% +$2.25M 0.01% 1392
2024
Q4 		$4.18M Buy
285,700
+101,100
+55% +$1.41M 0.01% 1560
2024
Q3 		$2.32M Sell
184,600
-52,181
-22% -$568K ﹤0.01% 1924
2024
Q2 		$2.02M Buy
236,781
+121,181
+105% +$1.08M ﹤0.01% 1884
2024
Q1 		$1.22M Buy
115,600
+100,900
+686% +$1.12M ﹤0.01% 2362
2023
Q4 		$153K Sell
14,700
-1,158
-7% -$9.23K ﹤0.01% 3210
2023
Q3 		$101K Sell
15,858
-246,279
-94% -$1.82M ﹤0.01% 3244
2023
Q2 		$2.27M Buy
262,137
+178,737
+214% +$1.6M ﹤0.01% 1921
2023
Q1 		$754K Sell
83,400
-36,600
-31% -$319K ﹤0.01% 2655
2022
Q4 		$943K Buy
120,000
+62,223
+108% +$437K ﹤0.01% 2571
2022
Q3 		$355K Buy
+57,777
New +$348K ﹤0.01% 3121
2022
Q2 		– Sell
-547,900
Closed -$3.59M – 4632
2022
Q1 		$3.59M Buy
547,900
+385,300
+237% +$3.43M ﹤0.01% 1813
2021
Q4 		$2.67M Buy
+162,600
New +$3.39M ﹤0.01% 1929
2021
Q2 		– Sell
-139,100
Closed -$4.39M – 3829
2021
Q1 		$4.39M Buy
139,100
+125,700
+938% +$5.11M 0.01% 1727
2020
Q4 		$633K Sell
13,400
-181,734
-93% -$8.44M ﹤0.01% 2718
2020
Q3 		$9.09M Sell
195,134
-544,000
-74% -$18.7M 0.01% 1209
2020
Q2 		$26.7M Sell
739,134
-60,613
-8% -$2.23M 0.02% 668
2020
Q1 		$28.4M Buy
799,747
+268,152
+50% +$11M 0.03% 605
2019
Q4 		$24.2M Buy
531,595
+156,088
+42% +$5.67M 0.02% 906
2019
Q3 		$9.31M Buy
375,507
+42,107
+13% +$1.05M 0.01% 1434
2019
Q2 		$7.33M Buy
333,400
+77,000
+30% +$1.41M 0.01% 1599
2019
Q1 		$4.16M Sell
256,400
-17,900
-7% -$278K ﹤0.01% 1928
2018
Q4 		$4.03M Sell
274,300
-102,500
-27% -$1.34M ﹤0.01% 1856
2018
Q3 		$5.92M Buy
376,800
+39,800
+12% +$570K 0.01% 1690
2018
Q2 		$4.98M Buy
+337,000
New +$5.22M 0.01% 1788

Other funds holding ZYME

EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
BNP Paribas Asset Management
BNP Paribas Asset Management Paris, France $86.1B AUM 29.11% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return

Renaissance Technologies's ZYME Position: Q1 2026 in Review

Renaissance Technologies sold out of Zymeworks (ZYME) in Q1 2026, closing a stake of 220,877 shares — an estimated $5.82M sold.

Renaissance Technologies first reported a position in ZYME in Q2 2018 and held it in 28 quarters. The position peaked at $28.4M in Q1 2020. 211 funds tracked by Wall St. Rank hold ZYME as of Q1 2026.

  • Renaissance Technologies reported no remaining Zymeworks position as of Q1 2026 after selling out during the quarter.
  • Renaissance Technologies sold 220,877 Zymeworks shares in Q1 2026, an estimated $5.82M.
  • Renaissance Technologies first reported a position in Zymeworks in Q2 2018 and held it in 28 quarters.
  • Renaissance Technologies's Zymeworks position peaked at $28.4M in Q1 2020.
  • 211 funds tracked by Wall St. Rank held Zymeworks as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.