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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
VAM
201
Verity Asset Management
North Carolina
$1.61M +$9.49K +117 +0.6%
BS
202
Banco Santander
Spain
$1.6M +$423K +5,218 +36%
Jones Financial Companies
203
Jones Financial Companies
Missouri
$1.59M -$150K -1,773 -9%
AWM
204
AE Wealth Management
Kansas
$1.58M -$3.24K -40 -0.2%
MMRF
205
Michelson Medical Research Foundation
California
$1.57M -$973K -12,000 -38%
MS
206
Maven Securities
Jersey
$1.55M +$666K +8,214 +75%
P
207
&Partners
Tennessee
$1.54M -$8.78K -104 -0.6%
Cerity Partners
208
Cerity Partners
New York
$1.51M +$82.4K +1,016 +6%
LB
209
Legacy Bridge
Iowa
$1.5M -$48.7K -600 -3%
CIBC Private Wealth Group
210
CIBC Private Wealth Group
Georgia
$1.46M +$103K +1,473 +8%
AIP
211
Ameritas Investment Partners
Nebraska
$1.46M -$4.06K -50 -0.3%
BP
212
Ballentine Partners
Massachusetts
$1.44M +$1.44M +17,771 New
PCP
213
Proficio Capital Partners
Massachusetts
$1.44M +$560K +6,915 +64%
DWP
214
Daymark Wealth Partners
Ohio
$1.44M – – –
RMDI
215
R.M. Davis Inc
Maine
$1.43M -$484K -5,972 -25%
FHA
216
Flagship Harbor Advisors
Massachusetts
$1.43M -$43.5K -536 -3%
SWM
217
Spire Wealth Management
Virginia
$1.42M +$21.7K +268 +2%
KPWS
218
Kestra Private Wealth Services
Texas
$1.42M -$49.8K -614 -3%
BFO
219
Biltmore Family Office
North Carolina
$1.41M -$59.6K -735 -4%
MIH
220
Meitav Investment House
Israel
$1.41M – – –
SC
221
Syon Capital
California
$1.4M -$1.1M -13,622 -44%
5SA
222
5th Street Advisors
Connecticut
$1.39M +$1.39M +17,190 New
DWM
223
Denver Wealth Management
Colorado
$1.39M +$201K +2,480 +17%
GS
224
GWN Securities
Florida
$1.37M +$1.37M +17,846 New
Carson Wealth (CWM LLC)
225
Carson Wealth (CWM LLC)
Nebraska
$1.35M +$293K +3,616 +28%
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