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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
SSB
151
Sandy Spring Bank
Maryland
$2.62M -$44.5K -549 -2%
AWMNY
152
Arcadia Wealth Management (New York)
New York
$2.58M -$73.4K -905 -3%
CCA
153
Conservest Capital Advisors
Pennsylvania
$2.56M -$47.8K -589 -2%
Creative Planning
154
Creative Planning
Kansas
$2.51M +$127K +1,567 +5%
SCM
155
SOL Capital Management
Maryland
$2.44M -$68.3K -842 -3%
AI
156
ArchPoint Investors
Florida
$2.42M +$71K +875 +3%
NFG
157
Nations Financial Group
Iowa
$2.39M -$35.8K -441 -1%
HAC
158
Harbor Advisory Corp
New Hampshire
$2.38M -$58.5K -721 -2%
GP
159
Greenline Partners
New York
$2.33M – – –
PFA
160
Pettinga Financial Advisors
Indiana
$2.32M -$19.9K -245 -0.8%
DCM
161
Dimension Capital Management
Florida
$2.26M +$862K +10,635 +62%
PA
162
Parallel Advisors
California
$2.22M -$1.23M -15,147 -36%
LJAC
163
L.J. Altfest & Co
New York
$2.21M -$85.6K -1,055 -4%
SCP
164
Stamos Capital Partners
California
$2.2M -$933K -11,504 -30%
ACP
165
Argyle Capital Partners
California
$2.19M +$372K +4,582 +20%
ECM
166
Eisler Capital Management
United Kingdom
$2.18M +$14.6K +180 +0.7%
LI
167
LMCG Investments
Massachusetts
$2.18M +$2.18M +26,819 New
HCP
168
Holt Capital Partners
Texas
$2.16M +$259K +3,195 +14%
MML Investors Services
169
MML Investors Services
Massachusetts
$2.13M -$2.19M -27,028 -51%
CA
170
Continental Advisors
Utah
$2.12M – – –
APF
171
Alaska Permanent Fund
Alaska
$2.11M – – –
EFS
172
Econ Financial Services
Pennsylvania
$2.06M +$310K +3,824 +18%
Mariner
173
Mariner
Kansas
$2.05M -$282K -3,475 -12%
Marshall Wace
174
Marshall Wace
United Kingdom
$2.03M +$1.38M +17,071 +215%
HCMT
175
Highland Capital Management (Tennessee)
Tennessee
$2.02M -$47K -579 -2%
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