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State Street SPDR S&P Biotech ETF

809 hedge funds and large institutions have $16.7B invested in State Street SPDR S&P Biotech ETF in 2026 Q1 according to their latest regulatory filings, with 106 funds opening new positions, 250 increasing their positions, 240 reducing their positions, and 93 closing their positions.

New
Increased
Maintained
Reduced
Closed

more ownership

Funds ownership:

more funds holding in top 10

Funds holding in top 10:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

1% more capital invested

Capital invested by funds: $16.5B → $16.7B (+$192M)

0% less funds holding

Funds holding: 812809 (-3)

54% less call options, than puts

Call options by funds: $2.19B | Put options by funds: $4.74B

Holders
809
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
22
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.19B
Puts
$4.74B
Net Calls
Net Calls Change

Top Buyers

1 +$570M
2 +$370M
3 +$212M
4
Barclays
Barclays
United Kingdom
+$118M
5
Morgan Stanley
Morgan Stanley
New York
+$105M

Top Sellers

1 -$771M
2 -$355M
3 -$256M
4
Citigroup
Citigroup
New York
-$233M
5
Two Sigma Investments
Two Sigma Investments
New York
-$177M
Name Holding Trade Value Shares
Change
Change in
Stake
MCM
126
MAI Capital Management
Ohio
$4.85M
FA
127
Fiduciary Alliance
South Carolina
$4.8M
BPWM
128
BCS Private Wealth Management
New Jersey
$4.76M
National Bank of Canada
129
National Bank of Canada
Quebec, Canada
$4.73M
BPA
130
Beacon Pointe Advisors
California
$4.67M
MHFA
131
Mission Hills Financial Advisory
California
$4.64M
CIEC
132
Crédit Industriel et Commercial
France
$4.55M
Millennium Management
133
Millennium Management
New York
$4.46M
FT
134
Fiduciary Trust
Massachusetts
$4.46M
LJAC
135
L.J. Altfest & Co
New York
$4.33M
BPIM
136
Brant Point Investment Management
New York
$4.33M
Franklin Resources
137
Franklin Resources
California
$4.31M
TRCT
138
Tower Research Capital (TRC)
New York
$4.2M
LBA
139
Letko, Brosseau & Associates
Quebec, Canada
$4.19M
PAG
140
Private Advisor Group
New Jersey
$4.15M
Cerity Partners
141
Cerity Partners
New York
$4.09M
SF
142
Summit Financial
New Jersey
$4.02M
CCA
143
Conservest Capital Advisors
Pennsylvania
$3.99M
MML Investors Services
144
MML Investors Services
Massachusetts
$3.97M
CICI
145
Capital Investment Counsel Inc
North Carolina
$3.93M
CAM
146
Cresset Asset Management
Illinois
$3.91M
MPA
147
Marvin & Palmer Associates
Delaware
$3.85M
HCP
148
Holt Capital Partners
Texas
$3.84M
RSCM
149
Rock Springs Capital Management
Maryland
$3.83M
AI
150
ArchPoint Investors
Florida
$3.82M