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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
BPIM
126
Brant Point Investment Management
New York
$3.99M -$50K -616 -1%
TS
127
Tamar Securities
California
$3.98M +$526K +6,481 +15%
TCA
128
Transcend Capital Advisors
New Jersey
$3.94M -$64.6K -797 -2%
CIEC
129
Crédit Industriel et Commercial
France
$3.85M +$2.63M +32,434 +216%
AFA
130
American Financial Advisors
Georgia
$3.85M -$67K -826 -2%
CIC
131
Carnegie Investment Counsel
Ohio
$3.76M -$3.62M -49,661 -49%
CIBC World Market
132
CIBC World Market
Ontario, Canada
$3.72M -$1.65M -20,319 -31%
BL
133
BCWM LLC
Kansas
$3.6M +$24.4K +301 +0.7%
QT
134
Quantbot Technologies
New York
$3.51M -$402K -4,955 -10%
IWM
135
IHT Wealth Management
Illinois
$3.49M -$2.14M -26,423 -38%
SRSA
136
S.R. Schill & Associates
Washington
$3.37M +$3.37M +41,595 New
FT
137
Fiduciary Trust
Massachusetts
$3.34M -$219K -2,699 -6%
LBA
138
Letko, Brosseau & Associates
Quebec, Canada
$3.24M -$239K -2,950 -7%
GJL
139
Gendell Jeffrey L
$3.15M – – –
CWM
140
CMH Wealth Management
New Hampshire
$3.08M -$15.1K -186 -0.5%
SC
141
Scotia Capital
Ontario, Canada
$3.04M -$2.03M -25,055 -40%
NA
142
NewEdge Advisors
Louisiana
$3.01M +$121K +1,490 +4%
MHFA
143
Mission Hills Financial Advisory
California
$2.95M +$19.5K +241 +0.7%
JWCA
144
J.W. Cole Advisors
Florida
$2.92M -$96.3K -1,187 -3%
CCMG
145
Clark Capital Management Group
Pennsylvania
$2.86M +$2.86M +35,267 New
IWC
146
Integrated Wealth Concepts
Massachusetts
$2.83M +$631K +7,780 +29%
BPC
147
Banque Pictet & Cie
Switzerland
$2.76M -$3.72M -45,814 -57%
MTWM
148
Masso Torrence Wealth Management
New Jersey
$2.71M +$521K +6,420 +24%
VanEck Associates
149
VanEck Associates
New York
$2.7M +$1.35M +16,622 +100%
Focus Partners Wealth
150
Focus Partners Wealth
Massachusetts
$2.67M -$419K -5,161 -14%
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