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State Street SPDR S&P Biotech ETF

808 hedge funds and large institutions have $16.5B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 228 funds opening new positions, 230 increasing their positions, 204 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

15.53% less ownership

Funds ownership: 214.6%199.06% (-16%)

51% less call options, than puts

Call options by funds: $3.12B | Put options by funds: $6.42B

Holders
808
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
19
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$3.12B
Puts
$6.42B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
GP
101
Geneva Partners
Wisconsin
$9.08M
PNC Financial Services Group
102
PNC Financial Services Group
Pennsylvania
$8.86M
HighTower Advisors
103
HighTower Advisors
Illinois
$8.84M
GAMH
104
Greenwoods Asset Management (HK)
Hong Kong
$8.32M
CGA
105
Crescent Grove Advisors
Illinois
$8.17M
TS
106
Tamar Securities
California
$8.02M
Fifth Third Bancorp
107
Fifth Third Bancorp
Ohio
$8M
MAM
108
Marotta Asset Management
Virginia
$7.99M
MTWSIF
109
Mivtachim The Workers Social Insurance Fund
Israel
$7.93M
BPC
110
Banque Pictet & Cie
Switzerland
$7.91M
KF
111
Krilogy Financial
Missouri
$7.81M
ONB
112
Old National Bancorp
Indiana
$7.57M
CI Investments Inc
113
CI Investments Inc
Ontario, Canada
$7.54M
PAA
114
Peregrine Asset Advisers
Oregon
$7.47M
NSLI
115
Nan Shan Life Insurance
Taiwan
$7.35M
FC
116
Fulcrum Capital
Washington
$6.95M
MA
117
Montag & Associates
Georgia
$6.85M
Nomura Asset Management
118
Nomura Asset Management
Japan
$6.79M
OAM
119
Oxford Asset Management
United Kingdom
$6.62M
PIA
120
Petredis Investment Advisors
Pennsylvania
$6.61M
Baird Financial Group
121
Baird Financial Group
Wisconsin
$6.6M
Balyasny Asset Management
122
Balyasny Asset Management
Illinois
$6.47M
OC
123
Oppenheimer & Co
New York
$6.44M
CIC
124
Carnegie Investment Counsel
Ohio
$6.16M
Capstone Investment Advisors
125
Capstone Investment Advisors
New York
$6.1M