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State Street SPDR S&P Biotech ETF

812 hedge funds and large institutions have $16.5B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 230 funds opening new positions, 232 increasing their positions, 204 reducing their positions, and 53 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

15.4% less ownership

Funds ownership: 214.61%199.2% (-15%)

51% less call options, than puts

Call options by funds: $3.12B | Put options by funds: $6.42B

Holders
812
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
19
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$3.12B
Puts
$6.42B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
SWM
101
Spire Wealth Management
Virginia
$9.15M
GP
102
Geneva Partners
Wisconsin
$9.08M
PNC Financial Services Group
103
PNC Financial Services Group
Pennsylvania
$8.86M
HighTower Advisors
104
HighTower Advisors
Illinois
$8.84M
GAMH
105
Greenwoods Asset Management (HK)
Hong Kong
$8.32M
CGA
106
Crescent Grove Advisors
Illinois
$8.17M
TS
107
Tamar Securities
California
$8.02M
Fifth Third Bancorp
108
Fifth Third Bancorp
Ohio
$8M
MAM
109
Marotta Asset Management
Virginia
$7.99M
MTWSIF
110
Mivtachim The Workers Social Insurance Fund
Israel
$7.93M
BPC
111
Banque Pictet & Cie
Switzerland
$7.91M
KF
112
Krilogy Financial
Missouri
$7.81M
ONB
113
Old National Bancorp
Indiana
$7.57M
CI Investments Inc
114
CI Investments Inc
Ontario, Canada
$7.54M
PAA
115
Peregrine Asset Advisers
Oregon
$7.47M
NSLI
116
Nan Shan Life Insurance
Taiwan
$7.35M
FC
117
Fulcrum Capital
Washington
$6.95M
MA
118
Montag & Associates
Georgia
$6.85M
Nomura Asset Management
119
Nomura Asset Management
Japan
$6.79M
OAM
120
Oxford Asset Management
United Kingdom
$6.62M
PIA
121
Petredis Investment Advisors
Pennsylvania
$6.61M
Baird Financial Group
122
Baird Financial Group
Wisconsin
$6.6M
Balyasny Asset Management
123
Balyasny Asset Management
Illinois
$6.47M
OC
124
Oppenheimer & Co
New York
$6.44M
CIC
125
Carnegie Investment Counsel
Ohio
$6.16M