SPDR S&P Biotech ETF
      
      
    
  672 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.
New
  Increased
  Maintained
  Reduced
  Closed
  more ownership
Funds ownership: →
less funds holding in top 10
Funds holding in top 10: →
less capital invested
Capital invested by funds: $ → $
less funds holding
Funds holding: →
35% less repeat investments, than reductions
Existing positions increased: 176 | Existing positions reduced: 269
40% less first-time investments, than exits
New positions opened: 72 | Existing positions closed: 120
50% less call options, than puts
Call options by funds: $1.08B | Put options by funds: $2.17B
    
      Holders
    
  
  
    
      
        
      
        672
      
    
      
    
  
    
      Holding in Top 10
    
  
  
    
      
        
      
        15
      
    
      
    
  
    
      Calls
    
  
  
    
      
        
      
        $1.08B
      
    
      
    
  
    
      Puts
    
  
  
    
      
        
      
        $2.17B
      
    
      
    
  
Top Buyers
| 1 | +$294M | |
| 2 | +$287M | |
| 3 | +$269M | |
| 4 |   
      JPMorgan Chase & Co
     
      
      
        New York
      
     | +$191M | 
| 5 | 
    MIFH
   
      Migdal Insurance & Financial Holdings
     
      
        Petach Tikva,
      
      
        Israel
      
     | +$85.2M | 
Top Sellers
| 1 | -$167M | |
| 2 | -$145M | |
| 3 | -$138M | |
| 4 | 
    RCM
   
      RA Capital Management
     
      
        Boston,
      
      
        Massachusetts
      
     | -$111M | 
| 5 | 
      Citadel Advisors
     
      
        Miami,
      
      
        Florida
      
     | -$61M | 
 
 
