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SPDR S&P Biotech ETF
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Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
SDH
751
Sloy Dahl & Holst
Washington
– -$207K -2,302 Closed
IAN
752
Integrated Advisors Network
Texas
– -$205K -2,281 Closed
MSAM
753
Moloney Securities Asset Management
Missouri
– -$205K -2,278 Closed
FFWA
754
FRG Family Wealth Advisors
Washington
– -$203K -2,250 Closed
GHAM
755
Gilman Hill Asset Management
Connecticut
– -$203K -2,250 Closed
MMG
756
Monetary Management Group
Missouri
– -$135K -1,500 Closed
MWA
757
Moser Wealth Advisors
Washington
– -$131K -1,452 Closed
PP
758
Paloma Partners
Connecticut
– -$95.5K -1,060 Closed
NIA
759
NBZ Investment Advisors
Tennessee
– -$90.1K -1,000 Closed
MG
760
MilWealth Group
Wisconsin
– -$64.6K -717 Closed
VAG
761
VisionPoint Advisory Group
Texas
– -$55.9K -611 Closed
OSNBOA
762
Old Second National Bank of Aurora
Illinois
– -$52.4K -582 Closed
CFGS
763
Concourse Financial Group Securities
Alabama
– -$47K -515 Closed
LDB
764
Lee, Danner & Bass
Tennessee
– -$37.7K -419 Closed
BCM
765
Blume Capital Management
California
– -$36K -400 Closed
AWM
766
Avior Wealth Management
Nebraska
– -$34.7K -385 Closed
HCA
767
Heck Capital Advisors
Wisconsin
– -$32.8K -364 Closed
KBFS
768
Kohmann Bosshard Financial Services
Ohio
– -$28.6K -317 Closed
SWC
769
Spectrum Wealth Counsel
Indiana
– -$27K -300 Closed
CP
770
Castleview Partners
Texas
– -$24.7K -270 Closed
QPBE
771
Quintet Private Bank (Europe)
Luxembourg
– -$24K -266 Closed
LFA
772
Legend Financial Advisors
Pennsylvania
– -$19.6K -218 Closed
JGIA
773
Jackson Grant Investment Advisers
Connecticut
– -$19.2K -213 Closed
CTC
774
Central Trust Company
Missouri
– -$15.9K -176 Closed
AWM
775
AllSquare Wealth Management
New York
– -$15.3K -170 Closed
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