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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
G
51
GenTrust
Florida
$15.4M +$22.7K +280 +0.1%
Capital Fund Management (CFM)
52
Capital Fund Management (CFM)
France
$15.1M +$15.1M +185,893 New
AWC
53
Abundance Wealth Counselors
Pennsylvania
$14.6M -$513K -6,267 -3%
UCMOK
54
United Capital Management of KS
Kansas
$14.5M +$496K +6,122 +4%
Rockefeller Capital Management
55
Rockefeller Capital Management
New York
$13.9M -$1.71M -21,124 -11%
Swedbank
56
Swedbank
Sweden
$13.8M -$4.91M -60,558 -26%
WTC
57
WhitTier Trust Company
Nevada
$13.5M +$512K +6,316 +4%
Barclays
58
Barclays
United Kingdom
$13.5M -$18M -222,542 -57%
PAG
59
Private Advisor Group
New Jersey
$13.4M -$2.7M -33,349 -17%
Citadel Advisors
60
Citadel Advisors
Florida
$13.3M -$61M -751,798 -82%
WAM
61
Weatherly Asset Management
California
$12.7M -$64.5K -795 -0.5%
Bank of Montreal
62
Bank of Montreal
Ontario, Canada
$12.6M -$7.56M -93,164 -37%
Cetera Investment Advisers
63
Cetera Investment Advisers
Illinois
$12.5M +$454K +5,604 +4%
NL
64
Nuveen LLC
North Carolina
$12.1M +$12.1M +149,658 New
Tudor Investment Corp
65
Tudor Investment Corp
Connecticut
$11.9M +$5.86M +72,307 +97%
LRPA
66
L. Roy Papp & Associates
Arizona
$11.9M -$367K -4,530 -3%
LI
67
LHM Inc
Utah
$11.7M +$1.61M +19,834 +16%
Allspring Global Investments
68
Allspring Global Investments
North Carolina
$11.5M -$1.03M -12,717 -8%
William Blair & Company
69
William Blair & Company
Illinois
$11.2M -$181K -2,233 -2%
Commonwealth Equity Services
70
Commonwealth Equity Services
Massachusetts
$11.1M -$1.22M -15,071 -10%
Hudson Bay Capital Management
71
Hudson Bay Capital Management
Connecticut
$11M +$11M +135,318 New
Northwestern Mutual Wealth Management
72
Northwestern Mutual Wealth Management
Wisconsin
$10.8M -$45.9M -565,801 -81%
SG Americas Securities
73
SG Americas Securities
New York
$10.4M +$1.84M +22,741 +21%
PEAK6
74
PEAK6
Illinois
$9.81M +$5.9M +72,746 +151%
PI
75
Parkside Investments
Illinois
$9.78M -$239K -2,950 -2%
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