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State Street SPDR S&P Biotech ETF

647 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 99 funds opening new positions, 150 increasing their positions, 239 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

more ownership

Funds ownership:

5% more funds holding

Funds holding: 619647 (+28)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

37% less repeat investments, than reductions

Existing positions increased: 150 | Existing positions reduced: 239

Holders
647
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
HT
676
Headlands Technologies
Illinois
VPA
677
Vernal Point Advisors
California
JJBC
678
James J. Burns & Company
New York
SIG
679
Sargent Investment Group
Maryland
NEPWA
680
New England Private Wealth Advisors
Massachusetts
BAAM
681
Baker Avenue Asset Management
California
IFPG
682
Intrepid Financial Planning Group
Indiana
ICP
683
Interchange Capital Partners
Pennsylvania
WPP
684
Whalerock Point Partners
Rhode Island
EFG
685
Embree Financial Group
Illinois
ML
686
McAdam LLC
Pennsylvania
CWM
687
ClientFirst Wealth Management
Arkansas
Manulife (Manufacturers Life Insurance)
688
Manulife (Manufacturers Life Insurance)
Ontario, Canada
AG
689
AlTi Global
New York
FTUS
690
Flow Traders U.S.
New York
HCMG
691
Howard Capital Management Group
California
CT
692
Colonial Trust
South Carolina
CLOS
693
Compagnie Lombard Odier SCmA
Switzerland
IUHSA
694
Itau Unibanco Holding S.A.
Brazil
BCV
695
Banque Cantonale Vaudoise
Switzerland
PSFG
696
Park Square Financial Group
Georgia
FC
697
Family CFO
California
GBA
698
Garrison Bradford & Associates
New York
TPWA
699
Twin Peaks Wealth Advisors
California
TSMHT
700
Thurston Springer Miller Herd & Titak
Indiana