State Street SPDR S&P Biotech ETF
655 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 151 increasing their positions, 242 reducing their positions, and 63 closing their positions.
New
Increased
Maintained
Reduced
Closed
more first-time investments, than exits
New positions opened: | Existing positions closed:
more funds holding in top 10
Funds holding in top 10: →
more capital invested
Capital invested by funds: $ → $
more ownership
Funds ownership: →
5% more funds holding
Funds holding: 624 → 655 (+31)
24% less call options, than puts
Call options by funds: $2.38B | Put options by funds: $3.15B
38% less repeat investments, than reductions
Existing positions increased: 151 | Existing positions reduced: 242
Holders
655
Holding in Top 10
18
Calls
$2.38B
Puts
$3.15B
Top Buyers
| 1 | +$418M | |
| 2 | +$261M | |
| 3 | +$248M | |
| 4 |
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
+$152M |
| 5 |
Barclays
London,
United Kingdom
|
+$134M |
Top Sellers
| 1 | -$168M | |
| 2 | -$154M | |
| 3 | -$148M | |
| 4 |
Jane Street
New York
|
-$114M |
| 5 |
BC
Broadwater Capital
Boston,
Massachusetts
|
-$90.8M |