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State Street SPDR S&P Biotech ETF

653 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 150 increasing their positions, 242 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

5% more funds holding

Funds holding: 622653 (+31)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 150 | Existing positions reduced: 242

Holders
653
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
QOP
676
Quinn Opportunity Partners
Virginia
GCP
677
Garda Capital Partners
Minnesota
YC
678
Yarbrough Capital
Tennessee
AWC
679
Abundance Wealth Counselors
Pennsylvania
QGA
680
Q Global Advisors
Texas
LFAS
681
Level Four Advisory Services
Texas
HT
682
Headlands Technologies
Illinois
VPA
683
Vernal Point Advisors
California
JJBC
684
James J. Burns & Company
New York
SIG
685
Sargent Investment Group
Maryland
NEPWA
686
New England Private Wealth Advisors
Massachusetts
BAAM
687
Baker Avenue Asset Management
California
IFPG
688
Intrepid Financial Planning Group
Indiana
ICP
689
Interchange Capital Partners
Pennsylvania
WPP
690
Whalerock Point Partners
Rhode Island
EFG
691
Embree Financial Group
Illinois
ML
692
McAdam LLC
Pennsylvania
CWM
693
ClientFirst Wealth Management
Arkansas
Manulife (Manufacturers Life Insurance)
694
Manulife (Manufacturers Life Insurance)
Ontario, Canada
AG
695
AlTi Global
New York
FTUS
696
Flow Traders U.S.
New York
HCMG
697
Howard Capital Management Group
California
CT
698
Colonial Trust
South Carolina
CLOS
699
Compagnie Lombard Odier SCmA
Switzerland
IUHSA
700
Itau Unibanco Holding S.A.
Brazil