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State Street SPDR S&P Biotech ETF

652 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 150 increasing their positions, 242 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

5% more funds holding

Funds holding: 621652 (+31)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 150 | Existing positions reduced: 242

Holders
652
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
GCP
676
Garda Capital Partners
Minnesota
YC
677
Yarbrough Capital
Tennessee
AWC
678
Abundance Wealth Counselors
Pennsylvania
QGA
679
Q Global Advisors
Texas
LFAS
680
Level Four Advisory Services
Texas
HT
681
Headlands Technologies
Illinois
VPA
682
Vernal Point Advisors
California
JJBC
683
James J. Burns & Company
New York
SIG
684
Sargent Investment Group
Maryland
NEPWA
685
New England Private Wealth Advisors
Massachusetts
BAAM
686
Baker Avenue Asset Management
California
IFPG
687
Intrepid Financial Planning Group
Indiana
ICP
688
Interchange Capital Partners
Pennsylvania
WPP
689
Whalerock Point Partners
Rhode Island
EFG
690
Embree Financial Group
Illinois
ML
691
McAdam LLC
Pennsylvania
CWM
692
ClientFirst Wealth Management
Arkansas
Manulife (Manufacturers Life Insurance)
693
Manulife (Manufacturers Life Insurance)
Ontario, Canada
AG
694
AlTi Global
New York
FTUS
695
Flow Traders U.S.
New York
HCMG
696
Howard Capital Management Group
California
CT
697
Colonial Trust
South Carolina
CLOS
698
Compagnie Lombard Odier SCmA
Switzerland
IUHSA
699
Itau Unibanco Holding S.A.
Brazil
BCV
700
Banque Cantonale Vaudoise
Switzerland