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State Street SPDR S&P Biotech ETF

656 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 151 increasing their positions, 243 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

59% more first-time investments, than exits

New positions opened: 100 | Existing positions closed: 63

20% more funds holding in top 10

Funds holding in top 10: 1518 (+3)

16% more capital invested

Capital invested by funds: $10.7B → $12.4B (+$1.69B)

14.41% more ownership

Funds ownership: 200.2%214.61% (+14%)

5% more funds holding

Funds holding: 625656 (+31)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 151 | Existing positions reduced: 243

Holders
656
Holders Change
+31
Holders Change %
+4.96%
% of All Funds
8.61%
Holding in Top 10
18
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+20%
% of All Funds
0.24%
New
100
Increased
151
Reduced
243
Closed
63
Calls
$2.38B
Puts
$3.15B
Net Calls
-$772M
Net Calls Change
+$5.45M
Name Holding Trade Value Shares
Change
Change in
Stake
1IA
651
1620 Investment Advisors
Massachusetts
$701
GWM
652
GSB Wealth Management
Connecticut
$701 +$270 +3 +75%
BWL
653
Bogart Wealth LLC
Virginia
$602
EWA
654
EverSource Wealth Advisors
Alabama
$601
GAG
655
Goodman Advisory Group
Massachusetts
$601
HI
656
Horizon Investments
North Carolina
$200 +$180 +2 New
HNB
657
Huntington National Bank
Ohio
$100
GA
658
Guerra Advisors
Florida
$100 +$90 +1 New
MIFH
659
Migdal Insurance & Financial Holdings
Israel
-$62.2M -750,000 Closed
PEAK6
660
PEAK6
Illinois
-$10.7M -118,991 Closed
Tudor Investment Corp
661
Tudor Investment Corp
Connecticut
-$6.55M -72,687 Closed
RFM
662
Royal Fund Management
Florida
-$5.6M -67,521 Closed
MMA
663
Mizuho Markets Americas
New York
-$5.35M -64,470 Closed
D.E. Shaw & Co
664
D.E. Shaw & Co
New York
-$5.15M -62,064 Closed
SB
665
SIG Brokerage
New York
-$5.41M -60,067 Closed
BL
666
BCWM LLC
Kansas
-$4.78M -57,663 Closed
LK
667
Lumbard & Kellner
New Hampshire
-$4.57M -55,089 Closed
Renaissance Technologies
668
Renaissance Technologies
New York
-$4.05M -48,800 Closed
QT
669
Quantbot Technologies
New York
-$3.95M -47,650 Closed
BBVA
670
Banco Bilbao Vizcaya Argentaria
Spain
-$3.17M -38,072 Closed
Citadel Advisors
671
Citadel Advisors
Florida
-$2.88M -31,980 Closed
EFS
672
Econ Financial Services
Pennsylvania
-$2.02M -24,367 Closed
Qube Research & Technologies (QRT)
673
Qube Research & Technologies (QRT)
United Kingdom
-$1.87M -22,595 Closed
Capital Fund Management (CFM)
674
Capital Fund Management (CFM)
France
-$1.79M -19,838 Closed
IMC Chicago
675
IMC Chicago
Illinois
-$1.55M -18,732 Closed