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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
FFA
651
Founders Financial Alliance
North Carolina
$2.11K – – –
AWM
652
Accredited Wealth Management
Kentucky
$2.03K -$62.5K -770 -97%
AF
653
Atala Financial
California
$2.03K – – –
SIC
654
SJS Investment Consulting
Ohio
$1.79K +$1.79K +22 New
IRC
655
Investors Research Corp
Georgia
$1.7K – – –
FRA
656
Front Row Advisors
California
$1.62K – – –
CPBTD
657
Central Pacific Bank - Trust Division
Hawaii
$1.3K – – –
NRG
658
Nemes Rush Group
Michigan
$1.22K – – –
GC
659
Garde Capital
Washington
$1.22K +$1.22K +15 New
C
660
Covestor
United Kingdom
$1K +$600 +6 +150%
PFBT
661
Parkside Financial Bank & Trust
Missouri
$975 – – –
WGS
662
Washington Growth Strategies
District of Columbia
$934 +$934 +81 New
FC
663
Fairscale Capital
New Hampshire
$892 – – –
MAS
664
MPWM Advisory Solutions
Georgia
$811 – – –
AC
665
AlphaCore Capital
California
$675 +$675 +8 New
CB
666
CNB Bank
Pennsylvania
$649 – – –
1IA
667
1620 Investment Advisors
Massachusetts
$568 – – –
EWA
668
EverSource Wealth Advisors
Alabama
$487 – – –
GAG
669
Goodman Advisory Group
Massachusetts
$487 +$487 +6 New
BWL
670
Bogart Wealth LLC
Virginia
$487 +$487 +6 New
CFS
671
CGC Financial Services
Oregon
$406 – – –
BCMLT
672
Beacon Capital Management LLC (Tennessee)
Tennessee
$406 +$406 +5 New
GWM
673
GSB Wealth Management
Connecticut
$350 +$350 +4 New
SIS
674
Sound Income Strategies
Florida
$2 -$2 – –
BCM
675
BlueCrest Capital Management
Jersey
– -$138M -1,532,882 Closed
25 26
27
28 29