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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
FMB
626
Field & Main Bank
Kentucky
$8.11K – – –
POIA
627
Pin Oak Investment Advisors
Texas
$8K – – –
RAM
628
Riggs Asset Management
Pennsylvania
$7.95K – – –
FIM
629
FWL Investment Management
Texas
$7.71K -$521K -6,418 -99%
SS
630
Sunbelt Securities
Texas
$7.64K – – –
FMII
631
Farmers & Merchants Investments Inc
Nebraska
$7.62K – – –
PG
632
Proffitt & Goodson
Tennessee
$7.3K – – –
BIA
633
Bell Investment Advisors
California
$7.14K -$9.25K -114 -56%
Russell Investments Group
634
Russell Investments Group
United Kingdom
$7.14K -$4.54K -56 -39%
PPA
635
Painted Porch Advisors
California
$6.65K – – –
LFG
636
Larson Financial Group
Missouri
$6.33K +$3.24K +40 +105%
AFG
637
Albion Financial Group
Utah
$6.08K -$136K -1,682 -96%
CSC
638
Caldwell Sutter Capital
California
$5.92K +$1.62K +20 +38%
CBT
639
Crews Bank & Trust
Florida
$4.87K – – –
MEG
640
Millstone Evans Group
Colorado
$4.46K – – –
GTAM
641
Global Trust Asset Management
Florida
$4.06K – – –
HWA
642
HHM Wealth Advisors
Tennessee
$4.06K – – –
OCM
643
Orion Capital Management
California
$4.06K – – –
MWM
644
MorganRosel Wealth Management
Colorado
$4.06K +$4.06K +50 New
MG
645
Mather Group
Illinois
$3.89K – – –
CAM
646
Costello Asset Management
Pennsylvania
$3K – – –
TFGT
647
TS Financial Group (TSFG)
Illinois
$3K – – –
AG
648
AmeriFlex Group
Nevada
$2.92K +$1.22K +15 +71%
RPA
649
Redwood Park Advisors
California
$2.92K – – –
CFD
650
Creative Financial Designs
Indiana
$2.35K -$9.01K -111 -79%
24 25
26
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