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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
PWMG
601
Prestige Wealth Management Group
New Jersey
$19.1K – – –
TSMHT
602
Thurston Springer Miller Herd & Titak
Indiana
$18.4K -$6.08K -75 -25%
S
603
Sachetta
Massachusetts
$18.2K +$7.71K +95 +73%
HWM
604
HighMark Wealth Management
Minnesota
$17.9K -$114K -1,404 -86%
BONH
605
Bank of New Hampshire
New Hampshire
$17.8K -$9.33K -115 -34%
Macquarie Group
606
Macquarie Group
Australia
$17.4K -$11K -136 -39%
CICI
607
Capital Investment Counsel Inc
North Carolina
$16.6K – – –
BAM
608
Bellevue Asset Management
Washington
$16.2K – – –
DPW
609
DiNuzzo Private Wealth
Pennsylvania
$16.2K +$16.2K +200 New
CWM
610
Consultiva Wealth Management
Puerto Rico
$16.2K +$16.2K +200 New
PP
611
Pacifica Partners
Canada
$15.6K – – –
Kayne Anderson Rudnick Investment Management
612
Kayne Anderson Rudnick Investment Management
California
$14.6K – – –
NSIM
613
North Star Investment Management
Illinois
$14.2K – – –
MMCM
614
Murphy & Mullick Capital Management
New York
$13.4K – – –
AssetMark Inc
615
AssetMark Inc
California
$12.2K -$50.3K -620 -80%
T
616
Tidemark
California
$12.2K -$3.65K -45 -23%
CA
617
Crewe Advisors
Utah
$12.2K – – –
SHIM
618
Stone House Investment Management
Pennsylvania
$12.2K +$12.2K +150 New
SWIM
619
Smallwood Wealth Investment Management
New Jersey
$10.9K +$10.9K +135 New
FGAM
620
Financial Gravity Asset Management
Texas
$9.73K +$9.73K +120 New
AWM
621
Activest Wealth Management
Florida
$9.47K -$9.23K -114 -49%
UCB
622
United Community Bank
South Carolina
$9.33K – – –
ST
623
Smithfield Trust
Pennsylvania
$9K – – –
SFG
624
Stonebridge Financial Group
Pennsylvania
$8.11K -$6.98K -86 -46%
RMP
625
Richards, Merrill & Peterson
Washington
$8.11K – – –
23 24
25
26 27