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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

613 hedge funds and large institutions have $9.73B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 270 reducing their positions, and 101 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
613
Holders Change
-58
Holders Change %
-8.64%
% of All Funds
8.22%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
270
Closed
101
Calls
$1.47B
Puts
$2.24B
Net Calls
-$777M
Net Calls Change
+$309M

Top Buyers

1
Goldman Sachs
Goldman Sachs
New York
+$414M
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$303M
3
Citigroup
Citigroup
New York
+$189M
4
Wells Fargo
Wells Fargo
California
+$61.8M
5
JFG
Jefferies Financial Group
New York
+$52.8M

Top Sellers

1
DFG
Demars Financial Group
Washington
-$258M
2
UBS Group
UBS Group
Switzerland
-$256M
3
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$207M
4
HIIFS
Harel Insurance Investments & Financial Services
Israel
-$48.7M
5
Squarepoint
Squarepoint
New York
-$40.1M
Name Holding Trade Value Shares
Change 		Shares
Change %
PG
576
Proffitt & Goodson
Tennessee
$7.46K – – –
BIA
577
Bell Investment Advisors
California
$7.3K – – –
PPA
578
Painted Porch Advisors
California
$6.8K – – –
FIM
579
FWL Investment Management
Texas
$5.97K -$1.91K -23 -24%
OWP
580
ORG Wealth Partners
Texas
$5.82K -$92.2K -1,108 -94%
TIM
581
Total Investment Management
Arizona
$5.08K +$5.08K +61 New
CBT
582
Crews Bank & Trust
Florida
$4.98K – – –
OCM
583
Orion Capital Management
California
$4.15K – – –
MWM
584
MorganRosel Wealth Management
Colorado
$4.15K – – –
HWA
585
HHM Wealth Advisors
Tennessee
$4.15K – – –
GTAM
586
Global Trust Asset Management
Florida
$4.15K – – –
RPA
587
Redwood Park Advisors
California
$4.15K +$1.16K +14 +39%
HNB
588
Hilltop National Bank
Wyoming
$4.15K +$4.15K +50 New
SSG
589
Summit Securities Group
New York
$4.15K +$4.15K +50 New
DF
590
Dunhill Financial
United Kingdom
$4.15K +$4.15K +50 New
JFA
591
JNBA Financial Advisors
Minnesota
$3.4K +$3.4K +41 New
CAM
592
Costello Asset Management
Pennsylvania
$3.07K – – –
AG
593
AmeriFlex Group
Nevada
$3.02K – – –
TFGT
594
TS Financial Group (TSFG)
Illinois
$3K – – –
RCM
595
Raleigh Capital Management
North Carolina
$2.74K +$2.74K +33 New
C
596
Covestor
United Kingdom
$2K +$1.05K +11 +110%
CTC
597
Central Trust Company
Missouri
$1.99K +$1.99K +24 New
FRA
598
Front Row Advisors
California
$1.66K – – –
MAWAG
599
Mid-American Wealth Advisory Group
Missouri
$1.66K +$1.66K +20 New
CPBTD
600
Central Pacific Bank - Trust Division
Hawaii
$1.33K – – –
22 23
24
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