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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
GBA
576
Garrison Bradford & Associates
New York
$39.5K +$39.5K +487 New
HNB
577
Huntington National Bank
Ohio
$37.3K -$73.2K – –
EB
578
Eastern Bank
Massachusetts
$36.7K -$1.7K -21 -4%
MFT
579
Moisand Fitzgerald Tamayo
Florida
$32.4K – – –
HR
580
Howe & Rusling
New York
$31.3K -$10.8K -133 -26%
OSAM
581
O'Shaughnessy Asset Management
Connecticut
$30.6K -$27.7K -341 -47%
AF
582
Allworth Financial
California
$29.9K +$6.32K +78 +27%
HCM
583
Hollencrest Capital Management
California
$29.2K – – –
DCM
584
Davis Capital Management
Florida
$28.5K – – –
FHA
585
First Horizon Advisors
Tennessee
$28.4K – – –
PWA
586
Provenance Wealth Advisors
Florida
$26.6K -$170K -2,100 -86%
GSWM
587
Golden State Wealth Management
California
$25.9K – – –
PWM
588
Provident Wealth Management
Tennessee
$25.1K +$24.3K +300 +3,000%
FWM
589
FSA Wealth Management
Massachusetts
$24.5K -$36.3K -447 -60%
OIA
590
Optimum Investment Advisors
Illinois
$24.3K -$32.4K -400 -57%
AAP
591
Arax Advisory Partners
Colorado
$24.3K – – –
GWSG
592
GPS Wealth Strategies Group
Colorado
$24.1K +$7.63K +94 +46%
TIM
593
Tortoise Investment Management
New York
$22.3K – – –
EWM
594
Evermay Wealth Management
Virginia
$22.3K – – –
GI
595
GAMMA Investing
California
$21.1K -$5.84K -72 -22%
RWPA
596
Richard W. Paul & Associates
Michigan
$20.3K – – –
CSPIA
597
Cary Street Partners Investment Advisory
Virginia
$19.9K – – –
TCA
598
Trifecta Capital Advisors
Illinois
$19.9K – – –
CAM
599
Creekmur Asset Management
Illinois
$19.8K – – –
SC
600
SouthState Corp
Florida
$19.5K +$19.5K +240 New
22 23
24
25 26