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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
VVP
501
Venture Visionary Partners
Ohio
$214K -$811 -10 -0.4%
TCOV
502
Trust Company of Vermont
Vermont
$214K -$4.06K -50 -2%
SIA
503
SeaBridge Investment Advisors
New Jersey
$213K -$42.1K -519 -17%
WA
504
WP Advisors
California
$212K – – –
Lido Advisors
505
Lido Advisors
California
$211K -$32.8K -404 -13%
EFS
506
Essex Financial Services
Connecticut
$208K +$208K +2,566 New
CAM
507
Covenant Asset Management
New Jersey
$208K -$23K -284 -10%
M
508
MOTCO
Texas
$207K – – –
SI
509
Sava Infond
Slovenia
$207K -$546K -6,730 -73%
MF
510
Montis Financial
Massachusetts
$207K – – –
Prudential Financial
511
Prudential Financial
New Jersey
$202K – – –
FM
512
Family Management
New York
$167K – – –
ACA
513
Aptus Capital Advisors
Alabama
$165K +$127K +1,572 +337%
TH
514
TCTC Holdings
Texas
$162K – – –
MIM
515
MetLife Investment Management
New Jersey
$156K +$156K +1,925 New
FC
516
Family CFO
California
$156K – – –
DWS
517
Dynamic Wealth Strategies
California
$154K +$154K +1,902 New
JHCP
518
Jackson Hole Capital Partners
Oklahoma
$149K – – –
VCM
519
Versant Capital Management
Arizona
$146K – – –
S
520
SignatureFD
Georgia
$145K -$44.5K -549 -24%
RCA
521
Runnymede Capital Advisors
Ohio
$145K – – –
ST
522
Skorpios Trust
Cyprus
$137K – – –
WP
523
WealthShield Partners
North Carolina
$136K -$15.7K -194 -10%
HDIM
524
Hanson & Doremus Investment Management
Vermont
$134K -$156K -1,924 -54%
MCM
525
Manchester Capital Management
Vermont
$131K – – –
19 20
21
22 23