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State Street SPDR S&P Biotech ETF

812 hedge funds and large institutions have $16.5B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 230 funds opening new positions, 232 increasing their positions, 204 reducing their positions, and 53 closing their positions.

New
Increased
Maintained
Reduced
Closed

334% more first-time investments, than exits

New positions opened: 230 | Existing positions closed: 53

33% more capital invested

Capital invested by funds: $12.4B → $16.5B (+$4.06B)

24% more funds holding

Funds holding: 655812 (+157)

14% more repeat investments, than reductions

Existing positions increased: 232 | Existing positions reduced: 204

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

15.4% less ownership

Funds ownership: 214.61%199.2% (-15%)

51% less call options, than puts

Call options by funds: $3.12B | Put options by funds: $6.42B

Holders
812
Holders Change
+157
Holders Change %
+23.97%
% of All Funds
9.88%
Holding in Top 10
19
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+5.56%
% of All Funds
0.23%
New
230
Increased
232
Reduced
204
Closed
53
Calls
$3.12B
Puts
$6.42B
Net Calls
-$3.31B
Net Calls Change
-$2.53B
Name Holding Trade Value Shares
Change
Change in
Stake
GC
476
Gruss & Co
Florida
$427K -$57.3K -500 -13%
MC
477
Mathes Company
New York
$423K
MIM
478
Miller Investment Management
Pennsylvania
$419K
IAN
479
Integrated Advisors Network
Texas
$411K +$142K +1,242 +58%
IPAM
480
Investment Partners Asset Management
New Jersey
$399K +$1.83K +16 +0.5%
CB
481
Commerce Bank
Missouri
$397K +$10.3K +90 +3%
KI
482
KTF Investments
California
$397K +$373K +3,254 New
FA
483
Fiduciary Alliance
South Carolina
$389K -$50.4K -440 -12%
SAM
484
Seelaus Asset Management
New Jersey
$388K -$5.73K -50 -2%
CCG
485
Coastwise Capital Group
California
$385K -$33.5K -292 -8%
CCG
486
Chatham Capital Group
Georgia
$384K -$144K -1,260 -29%
Vontobel Holding
487
Vontobel Holding
Switzerland
$383K +$104K +910 +41%
BCWM
488
Bartlett & Co Wealth Management
Ohio
$380K
JIP
489
Jaffetilchin Investment Partners
Florida
$380K +$51.3K +447 +17%
DA
490
Doliver Advisors
Texas
$379K -$5.73K -50 -2%
WSCM
491
Wellington Shields Capital Management
New York
$372K +$350K +3,050 New
GWM
492
Geneos Wealth Management
Colorado
$369K +$74.5K +650 +27%
AWA
493
Amplius Wealth Advisors
Pennsylvania
$368K +$1.15K +10 +0.3%
WANY
494
Wealthspire Advisors (New York)
New York
$365K +$243K +2,122 +243%
WF
495
Warner Financial
Maryland
$365K +$343K +2,995 New
WA
496
Waystone Advisors
Washington
$363K +$341K +2,974 New
MCC
497
Money Concepts Capital
Florida
$360K +$91.4K +797 +37%
WA
498
Waverly Advisors
Alabama
$356K +$335K +2,922 New
Northern Trust
499
Northern Trust
Illinois
$352K -$475K -4,139 -59%
NW
500
NewEdge Wealth
Pennsylvania
$348K -$74.6K -651 -19%