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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
IA
476
Integrity Alliance
Iowa
$236K +$236K +2,913 New
HNW
477
High Note Wealth
Minnesota
$235K -$137K -1,688 -37%
ESB
478
Essex Savings Bank
Connecticut
$234K +$40.6K +500 +21%
MIM
479
Macroview Investment Management
Maryland
$232K -$552K -6,811 -70%
SIC
480
Sterling Investment Counsel
New York
$232K +$232K +2,862 New
AFS
481
AFG Fiduciary Services
Massachusetts
$232K +$1.57K +21 +0.7%
AWM
482
Avaii Wealth Management
Wisconsin
$231K -$15.3K -189 -6%
PTC
483
Private Trust Company
Ohio
$230K +$15.1K +186 +7%
BCM
484
Bourgeon Capital Management
Connecticut
$229K +$13.2K +163 +6%
DWT
485
Dorsey & Whitney Trust
South Dakota
$227K – – –
GC
486
Grimes & Company
Massachusetts
$226K – – –
EWS
487
Eagle Wealth Strategies
New Jersey
$226K -$14K -173 -6%
GL
488
Graypoint LLC
New York
$225K +$81 +1 +0%
FFA
489
Fragasso Financial Advisors
Pennsylvania
$224K +$81 +1 +0%
PCM
490
Parsons Capital Management
Rhode Island
$223K – – –
GVAG
491
Great Valley Advisor Group
Delaware
$223K -$10.5K -129 -4%
SDAM
492
Shulman DeMeo Asset Management
New York
$223K – – –
PCM
493
Poehling Capital Management
Wisconsin
$222K -$7.79K -96 -3%
DI
494
Diligent Investors
California
$219K – – –
ACI
495
Alpha Cubed Investments
California
$218K -$254K -3,129 -54%
IAS
496
Insigneo Advisory Services
Florida
$217K +$217K +2,677 New
LMKC
497
L.M. Kohn & Company
Ohio
$217K +$8.11K +100 +4%
ICP
498
Interchange Capital Partners
Pennsylvania
$217K +$217K +2,672 New
EBA
499
Eagle Bay Advisors
New York
$215K -$26.4K -325 -11%
WW
500
Waterfront Wealth
Kansas
$215K – – –
18 19
20
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